Manchester City have the chance to extend their lead at the top of the table on Sunday.
Rivals Manchester United are not in action until Monday, so victory for City over Chelsea at The Emirates would take them 18 points clear.
The earlier game sees Brighton play host to out-of-form Arsenal – with Arsene Wenger in desperate need of three points. Victory for Chris Hughton’s side would take them into the top-half of the table.
See below for a preview on the game, including predictions from former England, Crystal Palace and Tottenham midfielder Andy Gray and our own Football Insider Graeme Bailey and bet365’s Steve Freeth.
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Brighton 13:30 Arsenal
TEAM NEWS: Brighton have a near fully fit squad with Steve SIdwell the only absentee. Jack Wilshere is a doubt for Arsenal, who are without Nacho Monreal, Santi Cazrola and Alexandre Lacazette.
KEY FACT: Arsenal are unbeaten in 34 PL matches against promoted sides
MATCH ODDS: Brighton 3/1 Draw 11/4 Arsenal 19/20
bet365 Pick: Draw @11/4
ANDY SAYS: I think Arsenal’s bad form will continue and Brighton will win this one…1-0
GRAEME SAYS: So often Arsenal do bounce back, and I think they might squeeze a win…1-2
FOOTBALLIndex – One to follow: Pierre-Emerick Aubameyang is a very good pick up for any portfolio
Man City 16:00 Chelsea
TEAM NEWS: Man City will give late fitness tests to Kyle Walker and Raheem Sterling, but Fernandinho is sidelined and Fabian Delph is suspended. Tiemoue Bakayoko, Ethan Ampadu and David Luiz are all ruled out for Chelsea but remain out for Chelsea but Ross Barkley returns to the squad.
KEY FACT: Manchester City have won their last 13 home matches
MATCH ODDS: Man City 4/7 Draw 10/3 Chelsea 21/4
bet365 Pick: Man City win & Both Teams To Score @21/10
ANDY SAYS: Easy City win, I don’t see any other result even thought it is Chelsea…3-0
GRAEME SAYS: I think this could be closer than some think
FOOTBALLIndex – One to follow: Eden Hazard remains a strong buy