The first Champions League semi-finalists will be decided on Tuesday and Manchester United are looking for another famous win in Barcelona.
One of United’s greatest ever moments came in the Nou Camp in 1999 when they beat Bayern Munich in the Champions League Final, with Ole Gunnar Solskjaer scoring the winner.
The Norwegian is now manager of United and this game against Barca marks the first time he has returned to the stadium since his now legendary winner 20-years ago.
And for United to progress they will need another big performance, and they will have to come from behind, like they did in the previous round at Paris Saint Germain, as Barcelona hold a 1-0 lead from the first-leg at Old Trafford.
The other semi-final sees Juventus host Ajax with the tie delicately poised at 1-1 from the first leg in Amsterdam.
We run through every game including predictions from former England, Crystal Palace and Tottenham midfielder Andy Gray, our own Football Insider Graeme Bailey and BoyleSports’ Lawrence Lyons.
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Barcelona 20:00 Manchester United (Agg 1-0)
TEAM NEWS: Rafinha misses out for Barcelona, who also have a doubt over defender Thomas Vermaelen.
United come into the game without the suspended Luke Shaw, who joins injured trio Eric Bailly, Antonio Valencia and Ander Herrera on the sidelines – but Alexis Sanchez and Nemanja Matic have travelled to Catalunya.
KEY FACT: Barcelona have never lost a home match against Manchester United in European competition
MATCH ODDS: Barcelona 4/11 Draw 4/1 Man Utd 15/2
BoyleSports pick: Half Time correct score 0-0 @ 11/4
ANDY SAYS: I think Man Utd’s run comes to an end here, easy Barca win…3-1
GRAEME SAYS: This would be a huge shock if Barca didn’t win, it will be close but United go out…1-1
Football Index – One to follow: Marcus Rashford – Has all the potential in the world, could easily lead the Index one day
Juventus 20:00 Ajax (Agg 1-1)
TEAM NEWS: Juventus are without Mario Mandzukic, Giorgio Chiellini, Martin Caceres and Mattia Perin, but they hope that Douglas Costa will be available.
Ajax have left-back Nicolas Tagliafico is suspended, whilst Hassane Bande is injured but they hope that Frenkie De Jong will be available.
KEY FACT: Juventus are unbeaten in their past 10 meetings with Ajax
MATCH ODDS: Juventus 3/4 Draw 13/5 Ajax 4/1
BoyleSports pick: Juve to win & over 1.5 goals @ Evens
ANDY SAYS: Close game but I see Juventus doing enough…2-1
GRAEME SAYS: Juventus class will see them home here, they will be too strong…3-1
Football Index – One to follow: Frenkie De Jong – A wonderful talent, plenty of value still in him