The Champions League gets underway on Tuesday with holders Liverpool facing a tough looking trip to Italy to begin their defence.
Jurgen Klopp takes his side to foot of Mount Vesuvius to face Napoli – one of the most daunting European trips any side can make.
Elsewhere in Group E, Red Bull Salzburg face Genk in Germany.
In Group H – Chelsea under Frank Lampard look to continue their good run of form as they host Valencia at Stamford Bridge, whilst the other game in the group sees last season’s surprise package Ajax welcome Lille to Amsterdam.
Group F is by far the toughest quartet, with Barcelona, Borussia Dortmund and Inter Milan all lining up against each other.
Barca travel to Dortmund for their opener whilst Inter host the other side in the group – Slavia Prague.
Benfica open their Group G account at home to Leipzig, whilst Lyon face Zenit in the other clash.
We run through every game including predictions from former England, Crystal Palace and Tottenham midfielder Andy Gray, our own Football Insider Graeme Bailey and BoyleSports’ Lawrence Lyons.
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FC Red Bull Salzburg 20:00 KRC Genk
MATCH ODDS: Salzburg 1/2 Draw 7/2 Genk 9/2
BoyleSports pick: Salzburg to win & over 1.5 goals @4/6
ANDY SAYS: Salzburg should be too good at home in this one…2-0
GRAEME SAYS: I quite fancy Genk to get something from this…1-1
Football Index – One to follow: Sander Berge – An outstanding midfield talent
Napoli 20:00 Liverpool
MATCH ODDS: Napoli 21/10 Draw 12/5 Liverpool 5/4
BoyleSports pick: Mo Salah to score first @5/1
ANDY SAYS: Won’t be easy but Liverpool get the win for me…1-2
GRAEME SAYS: I don’t see Liverpool not opening with a win…0-2
Football Index – One to follow: Hirving Lozano – Hugely talented Mexican who can make an impact
Inter Milan 17:55 Slavia Prague
MATCH ODDS: Inter 4/9 Draw 10/3 Slavia 13/2
BoyleSports pick: Romelu Lukaku to score two or more @5/1
ANDY SAYS: Won’t be too much of an issue here and Inter win…2-0
GRAEME SAYS: Inter could dish out a bit of a beating here…4-0
Football Index – One to follow: Romelu Lukaku – Can make big things happen in Inter
Borussia Dortmund 20:00 Barcelona
MATCH ODDS: Dortmund 19/10 Draw 11/4 Barcelona 6/5
BoyleSports pick: Barcelona to win @5/4
ANDY SAYS: Big win coming for Barca for me, their class will out…1-3
GRAEME SAYS: I think that we see Dortmund get off to a good start and shock Barca…2-1
Football Index – One to follow: Jadon Sancho – Outstanding young English talent
Lyon 17:55 Zenit St Petersburg
MATCH ODDS: Lyon 7/10 Draw 13/5 Zenit 4/1
BoyleSports pick: Moussa Dembele to score first @10/3
ANDY SAYS: Zenit are a decent side and I can see them claiming a draw here…1-1
GRAEME SAYS: I think that Lyon open up with a comfortable win…2-0
Football Index – One to follow: Moussa Dembele – Huge potential to push on and become a real star
Benfica 20:00 RB Leipzig
MATCH ODDS: Benfica 13/8 Draw 5/2 Leipzig 6/4
BoyleSports pick: Draw at Half Time @23/20
ANDY SAYS: I think this will be a good game with plenty of goals…2-2
GRAEME SAYS: I see Benfica being far too good here and a few goals coming…3-1
Football Index – One to follow: Ruben Dias – Outstanding young defender
Ajax 20:00 Lille
MATCH ODDS: Ajax 4/9 Draw 7/2 Lille 6/1
BoyleSports pick: Ajax Half Time/Full Time @6/5
ANDY SAYS: Ajax will begin with a win, no doubt…3-1
GRAEME SAYS: I believe that this could be a high scoring affair…2-2
Football Index – One to follow: Sergino Dest – Outstanding full-back and one to keep an eye on
Chelsea 20:00 Valencia
MATCH ODDS: Chelsea 3/4 Draw 14/5 Valencia 10/3
BoyleSports pick: Chelsea to win @3/4
ANDY SAYS: I think that Chelsea will be held here, in what is a tough game…1-1
GRAEME SAYS: Chelsea are on a high here and I think they get the win…2-0
Football Index – One to follow: Tammy Abraham – Is in great form and could become a real star