Only one game on Sunday, but little doubt it is the game of the weekend as Manchester United welcome bitter rivals and title favourites Liverpool to Old Trafford.
Liverpool are looking for a record equalling ninth successive win to open their season, whilst United are facing the prospect of dropping into the bottom three if they lose.
See below for a preview on the game, including predictions from former England, Crystal Palace and Tottenham midfielder Andy Gray and our own Football Insider Graeme Bailey and bet365’s Steve Freeth.
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Manchester United 16:30 Liverpool
TEAM NEWS: United come into the game with a huge injury list, which was added to this week with David De Gea and Paul Pogba ruled out. Also missing are Eric Bailly, Phil Jones, Aaron Wan-Bissaka, Diogo Dalot and Mason Greenwood – but they hope to have Luke Shaw, Anthony Martial and Jesse Lingard available.
Liverpool are boosted by the return of their number one Alisson, and they could also welcome back Xherdan Shaqiri and Joel Matip, whilst Mo Salah will be fit.
KEY FACT: Man Utd are unbeaten in their last five home league meetings with Liverpool
MATCH ODDS: Man Utd 17/4 Draw 14/5 Liverpool 13/20
bet365 Pick: Harry Maguire to score anytime @16/1
ANDY SAYS: Liverpool win here, no doubt for me…1-3
GRAEME SAYS: This could get embarassing for United, Liverpool could steam-roller them…0-4
Football Index – One to follow: Sadio Mane – One of the Premier League’s form players