Liverpool look to maintain their unbeaten start to the Premier League during an action-packed Saturday programme.
Jurgen Klopp’s side travel to The Midlands to take on Aston Villa, victory could put them nine points clear at the top, but defeat could allow champions Manchester City to close the gap.
And in a truly rare occurrence, Liverpool and City are both kicking off at three o’clock on Saturday. Whilst Liverpool are at Villa Park, City play host to third from bottom Southampton at the Etihad.
Should City slip-up then Chelsea have the chance to move into second as they face the trip to North London to take on bottom-of-the-table and win-less Watford.
Fifth placed Arsenal are looking to return to winning ways at the Emirates after being held by Crystal Palace last weekend, and they face a tricky looking task as they host Wolves
The day’s opening game takes place on the South Coast with Manchester United looking to continue their recent revival at Bournemouth.
Sheffield United could find themselves as high as fifth if results go their way and they beat Burnley at Bramall Lane.
West Ham are looking for their first win in over a month against a Newcastle side who have just two wins to their name this season.
Finally, Brighton are looking to make it consecutive victories as they welcome second bottom Norwich to the AMEX.
See below for a preview on the games, including predictions from former England, Crystal Palace and Tottenham midfielder Andy Gray and our own Football Insider Graeme Bailey and bet365’s Steve Freeth.
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AFC Bournemouth 12:30 Manchester United
TEAM NEWS: Dan Gosling, David Brooks, Charlie Daniels and Junior Stanislas all miss out for Bournemouth.
United are hoping Nemanja Matic, Luke Shaw, Marcus Rashford, Harry Maguire and Victor Lindelof will make the game but Paul Pogba, Eric Bailly, Axel Tuanzebe, Timothy Fosu-Mensah and Diogo Dalot are ruled out.
KEY FACT: Bournemouth are targeting their first win in five matches and their first goal in four fixtures
MATCH ODDS: Bournemouth 9/4 Draw 13/5 Man Utd 23/20
bet365 Pick: Anthony Martial 2+ Shots On Target @6/4
ANDY SAYS: Should be a very interesting game but I can see it playing out as a draw…1-1
GRAEME SAYS: Have not been too convinced by Bournemouth at certain parts this season and I think United might just come out on top…1-2
Football Index – One to follow: Marcus Rashford – Really hitting form and showing just how good he is
Arsenal 15:00 Wolverhampton Wanderers
TEAM NEWS: The only player ruled out for Arsenal is Reiss Nelson, but the likes of Mesut Ozil – who featured in midweek – will be hoping for a recall.
Wolves are without Wily Boly long-term but they hope Morgan Gibbs-White will return.
KEY FACT: Wolves have found the net in their last nine Premier League matches
MATCH ODDS: Arsenal 3/4 Draw 11/4 Wolves 15/4
bet365 Pick: Both Teams To Score @4/6
ANDY SAYS: Close game but I think Arsenal are back to winning ways with this one and they land the win…2-1
GRAEME SAYS: Two teams who are both very capable on their day, I think it plays out to be a draw…1-1
Football Index – One to follow: Raul Jimenez – Emerging a top quality number nine
Aston Villa 15:00 Liverpool
TEAM NEWS: Jack Grealish and Henri Lansbury should be available for Villa, but Jota is likely to remain sidelined.
Virgil van Dijk and Mo Salah are both set to feature for Liverpool, whilst they are a hopeful Naby Keita will make it – but Xherdan Shaqiri, Joel Matip and Nathaniel Clyne will be missing.
KEY FACT: Aston Villa have won only four of their 38 Premier League matches against sides starting the day top of the table
MATCH ODDS: Villa 8/1 Draw 4/1 Liverpool 1/3
bet365 Pick: Both Teams To Score @4/6
ANDY SAYS: I don’t see a major issue for Liverpool, they are so impressive and that will continue…1-3
GRAEME SAYS: Villa are improving every and I can see them getting something here off Liverpool…1-1
Football Index – One to follow: John McGinn – Looking like he has everything to go to the very top
Brighton & Hove Albion 15:00 Norwich City
TEAM NEWS: Bernardo and Jose Izquierdo are ruled out for Brighton, but Shane Duffy should be fit to feature.
Tim Krul, Ibrahim Amadou, Jamal Lewis and Mario Vrancic are all rated doubtful for Norwich, who are without Grant Hanley, Timm Klose and Christoph Zimmermann.
KEY FACT: This is the first ever Premier League meeting between these two sides
MATCH ODDS: Brighton 8/11 Draw 16/5 Norwich 10/3
bet365 Pick: Teemu Pukki to score anytime @7/4
ANDY SAYS: Norwich are struggling more than I though, and I like how Brighton are playing so home win all day in this one…2-0
GRAEME SAYS: Hard to put up an argument for Norwich to get something here and have
Football Index – One to follow: Neal Maupay – Has really proven he is Premier League material
Manchester City 15:00 Southampton
TEAM NEWS: Manchester City are still without Leroy Sane, Oleksandr Zinchenko, Rodri and Aymeric Laporte.
Ryan Bertrand is suspended for Southampton but they hope that Moussa Djenepo, Cedric Soares, Sofiane Boufal and Nathan Redmond could be available.
KEY FACT: Both of Southampton’s wins this season have come away from home
MATCH ODDS: Man City 1/14 Draw 12/1 Southampton 22/1
bet365 Pick: Man City win & Under 3.5 goals @6/4
ANDY SAYS: Comfortable win coming for City, and could be a big one…4-0
GRAEME SAYS: Coming off the back of their 9-0 loss, Southampton need a reaction – but it won’t be coming here…3-0
Football Index – One to follow: Raheem Sterling – One of the world’s best at the moment, no doubt
Sheffield United 15:00 Burnley
TEAM NEWS: Burnley are sweating over the fitness of Chris Wood and Phil Bardsley, but they are without Johann Gudmundsson and Danny Drinkwater.
The Blades are boosted by the fact they have a fully fit squad to choose from.
KEY FACT: This is the first Premier League meeting between these two sides
MATCH ODDS: Sheff Utd 6/5 Draw 11/5 Burnley 5/2
bet365 Pick: Both Teams Not To Score @19/20
ANDY SAYS: This could be a good game and I have to go with Sheff Utd as they are playing really well at the moment…2-1
GRAEME SAYS: Burnley and Sheff Utd are not too dissimilar and they could easily cancel each other out…0-0
Football Index – One to follow: Dwight McNeil – A superb talent, with a huge future
West Ham United 15:00 Newcastle United
TEAM NEWS: Lukasz Fabianski is out for West Ham, who also have major doubts over Winston Reid, Jack Wilshere and Michail Antonio.
Isaac Hayden returns from suspension for Newcastle, but Sean Longstaff begins his suspension for his red card last week. Andy Carroll and Fabian Schar remains major doubts.
KEY FACT: West Ham are looking for a third straight win over Newcastle for the first time since 1999
MATCH ODDS: West Ham 5/6 Draw 13/5 Newcastle 10/3
bet365 Pick: Under 2.5 goals @10/11
ANDY SAYS: I think Newcastle will get something here and hold West Ham to a draw…1-1
GRAEME SAYS: Has to be a home win, West Ham are good at home…2-0
Football Index – One to follow: Sean Longstaff – The Newcastle midfielder is really starting to look the part
Watford 17:30 Chelsea
TEAM NEWS: Watford will have Isaac Success available, but Troy Deeney and Danny Welbeck are sidelined, whilst Etienne Capoue, Ismaila Sarr and Tom Cleverley are major doubts.
Chelsea hope to have N’Golo Kante, Andreas Christensen and Ross Barkley available, but they will still be without Emerson, Ruben Loftus-Cheek, Antion Rudiger and Marco van Ginkel.
KEY FACT: Chelsea are aiming to secure back-to-back top-flight away victories over Watford for the first time
MATCH ODDS: Watford 4/1 Draw 10/3 Chelsea 8/13
bet365 Pick: Watford Double Chance @6/5
ANDY SAYS: Watford are just so poor at the moment, you have to go with Chelsea…0-2
GRAEME SAYS: Chelsea are playing some lovely stuff and I think the run continues here against an out-of-sorts Watford…1-3
Football Index – One to follow: Christian Pulisic – The American is showing just how good he is