Manchester City have the chance to not only progress but to win Group C on Wednesday evening.
City have a perfect record thus far and a win over Atalanta, with a draw in the other match will see them seal top spot.
Tottenham will be in good shape to progress if they can win at Red Star Belgrade, but Group B is all but tied up as Bayern Munich will progress with a win.
Group A has been dominated by Paris Saint Germain and they could progress with even a draw against Club Brugge, whilst Real Madrid know they can’t afford to slip up at home to Galatasaray.
Group D is almost all over, and victories for Juventus and Atletico Madrid will see them both progress.
We run through every game including predictions from former England, Crystal Palace and Tottenham midfielder Andy Gray, our own Football Insider Graeme Bailey and BoyleSports’ Lawrence Lyons.
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Paris Saint Germain 20:00 Club Brugge
MATCH ODDS: PSG 1/6 Draw 6/1 Brugge 14/1
BoyleSports pick: Mauro Icardi to score first @5/2
ANDY SAYS: PSG will keep their streak going and will progress with a win…2-0
GRAEME SAYS: PSG will be far too good for Brugge, no doubt…3-1
Football Index – One to follow: Mauro Icardi – Potentially a world class performer
Real Madrid 20:00 Galatasaray
MATCH ODDS: Real 2/11 Draw 6/1 Gala 14/1
BoyleSports pick: Real to win by two goals @16/5
ANDY SAYS: Real are not at their best but they need the win here and will get it…2-0
GRAEME SAYS: I can’t see Gala making too much of a challenge here, home win…2-0
Football Index – One to follow: Rodrygo – A brilliant young prospect for Real
Bayern Munich 17:55 Olympiakos
MATCH ODDS: Bayern 1/6 Draw 13/2 Olympiakos 14/1
BoyleSports pick: Robert Lewandowski to score in first half @11/10
ANDY SAYS: Bayern are very good team despite being manager-less and will win…3-1
GRAEME SAYS: Home win coming for the German giants, despite recent struggles…2-0
Football Index – One to follow: David Alaba – No better left sider in the world than the Austrian
Red Star Belgrade 20:00 Tottenham Hotspur
MATCH ODDS: Red Star 7/2 Draw 3/1 Spurs 4/6
BoyleSports pick: Both Teams To Score @4/6
ANDY SAYS: A trip to Belgrade is tough and I think Spurs might struggle in this one…1-0
GRAEME SAYS: Spurs are going through a bad patch but I think they take the win…1-2
Football Index – One to follow: Harry Winks – A hugely gifted midfielder
Atalanta 20:00 Manchester City
MATCH ODDS: Atalanta 4/1 Draw 4/1 Man City 1/2 1
BoyleSports pick: Man City to win 2-1 @8/1
ANDY SAYS: Not an issue for City in this one, they take the win…0-3
GRAEME SAYS: Not as easy as some think but still City to get the win…1-2
Football Index – One to follow: Duvan Zapata – A big talent up-front for Atalanta
Dinamo Zagreb 20:00 Shakhtar Donetsk
MATCH ODDS: Zagreb 6/5 Draw 12/5 Shakhtar 11/5
BoyleSports pick: Zagreb to win @6/5
ANDY SAYS: Close call here and I think they will cancel each other yet…1-1
GRAEME SAYS: Won’t be much in this one, but I think being at home Zagreb have the edge…2-1
Football Index – One to follow: Daniel Olmo – A very interesting talent for Zagreb
Lokomotiv Moscow 17:55 Juventus
MATCH ODDS: Lokomotiv 5/1 Draw 11/4 Juventus 6/10
BoyleSports pick: Juventus to win & Both Teams To Score @13/5
ANDY SAYS: Juventus will progress without too many issues…1-3
GRAEME SAYS: Moscow is not an easy trip for anyone but I think Juve edge the win…0-1
Football Index – One to follow: Rodrigo Bentacur – A brilliant midfielder
Bayer 04 Leverkusen 20:00 Atletico Madrid
MATCH ODDS: Bayer 15/8 Draw 21/10 Atletico 8/5
BoyleSports pick: Draw @21/10
ANDY SAYS: I don’t think this is an easy trip for Atletico and Bayer will get something…1-1
GRAEME SAYS: Atletico will join Juve in the next round by claiming the win here…0-2
Football Index – One to follow: Joao Felix – A supreme talent