Leicester City and Chelsea both have the chance to move into second spot in the Premier League on Saturday.
With the top-two – Liverpool and Manchester City – clashing on Sunday, Leicester have the chance to take advantage as they host Arsenal in the final game of the day.
Before Leicester play Chelsea host Crystal Palace in the opening game at Stamford Bridge, and victory for them would lift them into second place, possibly only for a few hours.
Tottenham host in-form Sheffield United and victory for Spurs could take them into the top-seven, but a Blades win would see them into fifth.
Seventh placed Bournemouth travel to the North East to face Newcastle United, who are looking for a second successive win which could lift them into the top-half of the table.
At the bottom and there is a six-point clash at St Mary’s seventeenth Everton face third from bottom Southampton – and victory for The Saints would put them level with The Toffeees, although they are just three points off Manchester United in tenth.
Burnley and West Ham clash at Turf Moor, with both sides desperate for a win. West Ham have not won since September whilst Burnley are looking to avoid a fourth successive defeat.
See below for a preview on the games, including predictions from former England, Crystal Palace and Tottenham midfielder Andy Gray and our own Football Insider Graeme Bailey and bet365’s Steve Freeth.
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Chelsea 12:30 Crystal Palace
TEAM NEWS: Palace come into the game without Connor Wickham and Mamadou Sakho, but they hope Cheikhou Kouyate, Gary Cahill, Andros Townsend and James McArthur will be available.
Chelsea hope to have Ross Barkley and Mason Mount available, but Jorginho is suspended. Antonio Rudiger, Ruben Loftus-Cheek and Marco van Ginkel remain sidelined.
KEY FACT: Frank Lampard can become the seventh English manager to win six consecutive Premier League matches
MATCH ODDS: Chelsea 1/3 Draw 4/1 Palace 9/1
bet365 Pick: Both Teams To Score @4/5
ANDY SAYS: Chelsea are playing so well, I don’t see how they don’t beat my former team…3-1
GRAEME SAYS: Frank Lampard has chance to take his side into second and they will do it here…2-0
Football Index – One to follow: Christian Pulisic – One of the Premier League’s form players
Burnley 15:00 West Ham United
TEAM NEWS: Burnley will give a late fitness test to Chris Wood, but Danny Drinkwater and Johann Berg Gudmundsson remain sidelined.
Lukasz Fabianski and Winston Reid remain sidelined, but Jack Wilshere and Michail Antonio could feature for West Ham.
KEY FACT: Burnley have won two of their last three Premier League matches against West Ham
MATCH ODDS: Burnley 5/4 Draw 5/2 West Ham 21/10
bet365 Pick: Both Teams Not To Score @6/5
ANDY SAYS: This is a close game but I think Burnley get the big win, as West Ham are not in a good place…2-1
GRAEME SAYS: This game could really go either way but I am saying draw…1-1
Football Index – One to follow: Manuel Lanzini – A fantastic talent, could be playing higher
Newcastle United 15:00 AFC Bournemouth
St. James’ Park
TEAM NEWS: Sean Longstaff remains suspended for Newcastle, who are also without Matt Ritchie, but they hope defenders Fabian Schar and Florian Lejeune will return.
Dan Gosling has a chance of returning for Bournemouth, who still have a host of names who are sidelined through injury in the shape of Andrew Surman, David Brooks, Charlie Daniels and Junior Stanislas. Jefferson Lerma is suspended.
KEY FACT: Newcastle are looking to secure back-to-back Premier League victories for the first time since April
MATCH ODDS: Newcastle 8/5 Draw 9/4 Bournemouth 9/5
bet365 Pick: Over 2.5 goals @Evens
ANDY SAYS: Newcastle are not as bad as some think and they will get two wins in-a-row here…2-1
GRAEME SAYS: Bournemouth need a win here and I think they get it, but will be a close game…1-2
Football Index – One to follow: Callum Wilson – Could still be set for a huge move
Southampton 15:00 Everton
St. Mary’s Stadium
TEAM NEWS: Cedric Soares should be fit to return for Southampton, but his fellow full-back Ryan Bertrand is suspended.
Andre Gomes has joined Jean-Philippe Gbamin on the sidelines for Everton, who are also likely to be without Fabian Delph and Bernard.
KEY FACT: Eleven of Southampton’s 12 Premier League wins against Everton have come at home
MATCH ODDS: Southampton 19/10 Draw 23/10 Everton 29/20
bet365 Pick: Over 2.5 goals @10/11
ANDY SAYS: Everton have been playing better than their results suggest and I can see them getting the win here…1-2
GRAEME SAYS: Southampton are not a good team and I see Everton getting the three points…0-2
Football Index – One to follow: Richarlison – A special talent, an outstanding player
Tottenham Hotspur 15:00 Sheffield United
Tottenham Hotspur Stadium
TEAM NEWS: Erik Lamela has a chance of making the game, but Hugo Lloris and Jan Vertonghen are sidelined for Spurs.
Sheffield United will give a late fitness test to John Egan, and if he is fit then Sheffield United will have a fully fit squad to choose from.
KEY FACT: Tottenham have never lost in the Premier League to Sheffield United
MATCH ODDS: Spurs 4/7 Draw 3/1 Sheff Utd 5/1
bet365 Pick: Tottenham to win & Under 2.5 goals @4/5
ANDY SAYS: My former team will get the win here, I think they will have too much…2-0
GRAEME SAYS: I am not convinced by Spurs here but I think they will just about get the job done…2-1
Football Index – One to follow: Dele Alli – Getting back to form, showing what a player he really is
Leicester City 17:30 Arsenal
King Power Stadium
TEAM NEWS: Dani Ceballos and Granit Xhaka are both ruled out for Arsenal.
Leicester have a near fully fit squad with only Matt James missing from Brendan Rodgers’s squad.
KEY FACT: Leicester have the chance to win a third consecutive game against Arsenal
MATCH ODDS: Leicester Evens Draw 11/4 Arsenal 5/2
bet365 Pick: Leicester to win @Evens
ANDY SAYS: Leicester are one of the best teams around at the moment an they will beat Arsenal here…3-1
GRAEME SAYS: Leicester are such an impressive team and they will continue their good form here…2-0
Football Index – One to follow: James Maddison – Nobody has been better in the Premier League this season