There are just three games on Sunday, but they big ones with holders Manchester City, Liverpool and Manchester United all in action.
All are facing lower league opposition with City hosting Championship Fulham, United travelling to Tranmere and Liverpool facing a trip to Shrewsbury.
We run through every game including predictions from former England, Crystal Palace and Tottenham midfielder Andy Gray, our own Football Insider Graeme Bailey and BoyleSports’ Lawrence Lyons.
Manchester City 13:00 Fulham
MATCH ODDS: Man City 1/10 Draw 10/1 Fulham 25/1
BoyleSports pick: Man City to win both halves @5/6
ANDY SAYS: Man City don’t lose their grip on the FA Cup just yet, home win…3-0
GRAEME SAYS: Fulham are not a bad team, but they can’t stop City…2-0
Tranmere Rovers 15:00 Manchester United
MATCH ODDS: Tranmere 13/2 Draw 15/4 Man Utd 2/5
BoyleSports pick: Mason Greenwood to score first @7/2
ANDY SAYS: Poor pitch at Tranmere and United will suffer, big shock coming…2-1
GRAEME SAYS: I believe that United will go through but it won’t be easy…1-2
Shrewsbury Town 17:00 Liverpool
MATCH ODDS: Shrewsbury 11/2 Draw 7/2 Liverpool 1/2
BoyleSports pick: Divock Origi to score anytime @Evens
ANDY SAYS: Even a weakened Liverpool team will be far too strong in this one…1-4
GRAEME SAYS: Liverpool are going through here, no doubt…0-3