League Cup holders Manchester United continue their defence of the trophy on Wednesday evening.
United face the only non-Premier League side left in the draw in the shape of Championship Bristol City at Ashton Gate.
The final quarter-final clash sees Chelsea play host to Bournemouth.
See below for a preview on the games, including predictions from former England, Crystal Palace and Tottenham ace Andy Gray, leading agent and former Man City midfielder Barry Silkman and our own Football Insider Graeme Bailey together with everything you need to know from the bookies – with BoyleSports’s Lawrence Lyons.
Chelsea 19:45 AFC Bournemouth
TEAM NEWS: Chelsea are set to make a raft of changes with Kenedy, Michy Batshuayi, Callum Hudson-Odoi, Dujon Sterling and Ethan Ampadu are also set to feature. Bournemouth are without injured duo Charlie Daniels and Josh King.
KEY FACT: Bournemouth have only won one of their last nine meetings with Chelsea
MATCH ODDS: Chelsea 2/7 Draw 9/2 Bournemouth 11/1
ANDY SAYS: Comfortable home win, don’t see Chelsea not winning…3-0
GRAEME SAYS: Second string Chelsea side but still too much for Bournemouth…2-0
SILKY SAYS: Home win all the way and without too many problems…3-0
BOYLESPORTS PICK: Chelsea To Win Both Halves @9/5
FOOTBALLIndex – One to follow: Andreas Christensen is on the rise at £1.64
Bristol City 20:00 Manchester United
TEAM NEWS: Henrikh Mkhitaryan is set for a recall, whilst Paul Pogba is available again following suspension.
KEY FACT: This is the first time these two have met since 1980
MATCH ODDS: Bristol City 5/1 Draw 10/3 Man Utd 8/15
ANDY SAYS: I don’t see United being troubled too much in this one…0-3
GRAEME SAYS: Won’t be easy for United, just about get through…1-2
SILKY SAYS: Easy win for United here..0-3
BOYLESPORTS PICK: Zlatan Ibrahimovic to score anytime @4/5
FOOTBALLIndex – One to follow: Still in the top ten, Paul Pogba is worth £4.56