Manchester City, Tottenham Hotspur and Liverpool could all win their Champions League groups on Tuesday evening.
Man City and Tottenham have already secured their places in the knockout phase, but Liverpool are yet to finalise their last 16 spot.
Liverpool travel to Sevilla knowing victory will see them through and also seal top-spot, whilst even a draw will suffice if Spartak Moscow lose.
“We will have to show our new maturity 100 per cent in this (Seville) atmosphere,” said Reds boss Jurgen Klopp.
“We do not need to run in only one direction and win in the first second. We have to show how the last games were against a quality opponent.”
Man City will seal top spot if they beat Feyenoord and Shakhtar Donetsk do not do the same against Napoli. A draw will also be enough for City if Shakthar lose.
Despite City’s dominance, their boss Pep Guardiola does not see them as favourites to win.
“it doesn’t mean we are favourites to win the Champions League but it’s nice. It means we are doing some things very well,” he said.
“But obviously people usually say the favourite teams are Barcelona, Bayern Munich, Real Madrid and others. But that people put us there, is a big honour. That does not mean we have done anything, because we haven’t.”
Tottenham, who face Borussia Dortmund in Germany, just need to match Real Madrid’s result against APOEL.
Despite already being through, coach Maurio Pochettino won’t be playing a weakened side.
“We are going to play with our best team, fresh players and like always never taking risk with them. The most important thing is the health of the players. We analyse a lot. Maybe for some people it’s hard to understand but we have all the knowledge.”
See below for a run-down on the games, including predictions from leading agent Barry Silkman and our own Football Insider Graeme Bailey together with everything you need to know from the bookies – with BoyleSports’s Leon Blanche.
Sevilla 19:45 Liverpool
Ramon Sanchez Pizjuan
TEAM NEWS: Joel Matip and Nathaniel Clyne are missing for Liverpool, who otherwise have a near fully fit squad. Nicolas Pareja, Daniel Carrico and Walter Montoya are all missing for Sevilla.
KEY FACT: Both teams qualify for last 16 if they win
MATCH ODDS: Sevilla 9/4 Draw 13/5 Liverpool 6/4
ANDY SAYS: I think Liverpool can get the win they need here…1-2
GRAEME SAYS: A close call, I think these two are quite evenly matched…1-1
SILKY SAYS: Won’t be much in it but I believe Sevilla are a very strong team and will win…2-1
BOYLESPORTS PICK: Draw @13/5
FOOTBALLIndex – One to follow: Philippe Coutinho is just over £5 – still looks good value to us
Manchester City 19:45 Feyenoord
TEAM NEWS: John Stones and Benjamin Mendy are both sidelined for City. For Feyenoord, Eric Botteghin and Jan-Arie van der Heijden are both injured but Karim El Ahmadi is suspended.
KEY FACT: Feyenoord cannot finish in the top two
MATCH ODDS: Man City 1/7 Draw 8/1 Feyenoord 18/1
ANDY SAYS: Comfortable home win, don’t see anything but a comfortable success…4-0
GRAEME SAYS: Could be a real hammering on the cards here…5-0
SILKY SAYS: City win, little doubt about it, and a comfortable win…4-0
BOYLESPORTS PICK: Man City -1 @4/11
FOOTBALLIndex – One to follow: Kevin De Bruyne is now just over £4 – still a wonderful buy
Borussia Dortmund 19:45 Tottenham Hotspur
Sugnal Iduna Park
TEAM NEWS: Victor Wanyama and Toby Alderweireld are both sidelined for Spurs, whilst Lukasz Piszczek Sebastian Rode and Erik Durm are missing for Dortmund.
KEY FACT: Dortmund must win to stay in contention
MATCH ODDS: Dortmund Evens Draw 11/4 Spurs 13/5
ANDY SAYS: I think my old team might just have enough to see this one out…1-2
GRAEME SAYS: I think Dortmund might just keep their hopes alive with a win…2-1
SILKY SAYS: Close call and I think this one will end up being a draw…1-1
BOYLESPORTS PICK: Spurs win @13/5
FOOTBALLIndex – One to follow: Dele Alli at £4 looks a great buy