Tottenham and Manchester City both look to continue their perfect starts to their Champions League campaigns on Tuesday.
Spurs sealed an opening win over Borussia Dortmund in Group H and they face Cyrpiot champions APOEL Nicosia on Tuesday.
Knowing they face a double-header against Real Madrid after this match, boss Mauricio Pochettino admits they need to win in Cyprus.
“After doing so well against Borussia Dortmund, it is a must win (against APOEL),” said the Argentine.
“The fans expect us to win the game but the Champions League is so tough. I have watched APOEL play in their local league and against Real Madrid.
“They have good players and it will be a very dangerous game. We need to be focused.”
City opened with victory over Feyenoord and they are looking to follow that up at home to Shakhtar Donetsk and Pep Guardiola insists the Ukrainian giants – who beat Napoli in their opener – will provide a stern test.
“The players are going to see how good they are and hopefully I can convince them to take Shakhtar seriously,” he said.
“Shakhtar Donetsk from my experience deserve all the credit.”
In Group E, every team is on one point and Liverpool are hoping to take something from their tricky looking trip to Moscow to face Spartak.
“We are an offensive-orientated team but this is about Champions League football – we need results,” Klopp said,
“The balance has to be right. It is not about being spectacular, it is about being good and being clinical and having perfect timing and perfect protection. We cannot just bring all the artists but if it fits together we will do it.”
Elsewhere, champions Real Madrid travel to Dortmund looking to maintain their perfect start to their defence.
Last season’s surprise package Monaco entertain Porto, Napoli face Feyenoord, Besiktas take on RB Leipzig and Sevilla welcome Slovenia’s Maribor.
See below for a run-down on the games, including predictions from former England, Crystal Palace and Tottenham midfielder Andy Gray, leading agent Barry Silkman and our own Football Insider Graeme Bailey together with everything you need to know from the bookies – with BoyleSports’s Leon Blanche.
GROUP H
APOEL 19:45 Tottenham
GPS Stadium
TEAM NEWS: Christian Eriksen misses the trip through illness and joins Mousa Dembele, Danny Rose, Victor Wanyama and Erik Lamela on the sidelines. Dele Alli and Jan Vertonghen are both suspended.
KEY FACT: No Cypriot side has beaten English opposition in European competition in 12 attempts
MATCH ODDS: APOEL 10/1 Draw 4/1 Spurs 1/3
ANDY SAYS: Spurs impressive away from home and far too good here…1-3
GRAEME SAYS: Tottenham are clever and won’t be caught out here…0-2
SILKY SAYS: Comfortable Spurs win for sure…0-3
BOYLESPORTS PICK: Harry Kane first goal @7/4
FOOTBALLIndex – One to follow: Dele Alli at £3.30 – no brainer!
GROUP F
Man. City 19:45 Shakhtar Donetsk
Etihad Stadium
TEAM NEWS: Ilkay Gundogan and Vincent Kompany both miss out. Benjamin Mendy is to have a late fitness test with Danilo ready to replace him.
KEY FACT: No Ukrainian club has ever won an away game in the Champions League against English opposition
MATCH ODDS: Man City 1/5 Draw 6/1 Shakhtar 12/1
ANDY SAYS: Man City, no problems here and comfortable win…3-0
GRAEME SAYS: Could be any score here really – easy victory…4-0
SILKY SAYS: Don’t see how City will falter here, home win all the way…3-0
BOYLESPORTS PICK: Gabriel Jesus to score first @3/1
FOOTBALLIndex – One to follow: Gabriel Jesus at just over £3 is a good buy
GROUP E
Spartak Moscow 19:45 Liverpool
Otkrytie Arena
TEAM NEWS: Sadio Mane will start following his domestic ban. Joe Gomez serves a one-match ban after being sent-off against Sevilla.
KEY FACT: Spartak have won only two of their past 17 home games in the Champions League
MATCH ODDS: Spartak 4/1 Draw 3/1 Liverpool 4/6
ANDY SAYS: I can see Liverpool getting the three points here, but it won’t be easy…1-2
GRAEME SAYS: Tough one to call, Liverpool have the quality but I think they might struggle…1-1
SILKY SAYS: Won’t be an easy trip, never is to Russia so I think the home side might hold Liverpool…1-1
BOYLESPORTS PICK: Liverpool to win and both teams to score @11/5
FOOTBALLIndex – One to follow: Sadio Mane – a quality performer and just over £3