Wednesday’s Champions League action sees favourites Manchester City travel to Real Madrid for the first leg of their last 16 clash.

Pep Guardiola’s takes his side to the Santiago Bernabeu determined to get a result to take back to the Etihad next month.

The night’s other clash sees Lyon host Italian champions Juventus.

We run through every game including predictions from our own Football Insider Graeme Bailey and BoyleSports’ Lawrence Lyons.

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Lyon 20:00 Juventus
Groupama Stadium

TEAM NEWS: Lyon come into the game without Youssouf Kone, Rafael, Memhis Depay and Jeff Reine-Adelaide. | Juventus are missing Douglas Costa and Meriah Demiral, whilst Sami Khedira and Gonzalo Higuain are doubtful.
MATCH ODDS: Lyon 3/1 Draw 23/10 Juventus Evens
BoyleSports pick: Cristiano Ronaldo to score first @9/4
GRAEME SAYS: Juventus are a class act and they come away with the win…0-2
Football Index – One to follow: Miralem Pjanic – Wonderful talent in Juve’s midfield

Real Madrid 20:00 Manchester City
Santiago Bernabeu

TEAM NEWS: Real Madrid are missing Marcos Asensio and Eden Hazard. | City come into the game with a near fully fit squad with only Leroy Sane missing.
MATCH ODDS: Real 15/8 Draw 11/4 City 13/10
BoyleSports pick: Real Madrid Half Time/Full Time @15/4
GRAEME SAYS: I think that City can take a win here, as they will step up for Pep…0-2
Football Index – One to follow: Kevin De Bruyne – Will prove he is the best in the world