The final two games of Easter take place on Sunday with two matches in the capital.
The opening game sees Arsenal host second from bottom Stoke, who are in desperate need of victory.
The second and final game is a big one, as Tottenham make the trip across London to face rivals Chelsea.
See below for a preview on the games, including predictions from former England, Crystal Palace and Tottenham midfielder Andy Gray and our own Football Insider Graeme Bailey and bet365’s Steve Freeth.
Arsenal 13:30 Stoke City
Emirates Stadium
TEAM NEWS: Jack Wilshere and Alexandre Lacazette will both be given checks before kick-off to see if they can make it. Eric Maxim Choupo-Moting misses out through injury, whilst Charlie Adam is suspended, but Mame Biram Diouf could feature.
KEY FACT: A competition-high 72.9 per cent of Arsenal’s Premier League points this season have been won in home matches
MATCH ODDS: Arsenal 3/10 Draw 5/1 Stoke 10/1
bet365 Pick: Both Teams To Score @3/4
ANDY SAYS: I can see an upset here, Stoke to claim a huge win…1-2
GRAEME SAYS: Do Arsenal have the heart for this? Not sure…1-1
FOOTBALLIndex – One to follow: Jack Wilshere looks a good buy on the Index
Chelsea 16:00 Tottenham Hotspur
Stamford Bridge
TEAM NEWS: Tottenham are hoping that Harry Kane could make the game, but he is more likely to miss out. Toby Alderweireld is set to feature, but Harry Winks is sidelined. Thibaut Courtois and Andreas Christensen are expected to play despite carrying knocks but Ross Barkley and David Luiz will miss out.
KEY FACT: Spurs have won more points in PL London derbies this season than any other side
MATCH ODDS: Chelsea 7/5 Draw 23/10 Spurs 9/4
bet365 Pick: Both Teams To Score @Evens
ANDY SAYS: I see Chelsea landing a decent win in this one…3-1
GRAEME SAYS: Hard to separate these two, have to say draw…1-1
FOOTBALLIndex – One to follow: Eden Hazard, still world-class, still a great buy