Friday night football offers Liverpool the chance to return to the top of the Premier League.
Leaders Manchester City are not in league action this weekend so that gives Liverpool the chance to overtake them.
To do so move Liverpool need to take three points from Southampton – who are also in need of points as they are just five points above the drop-zone.
See below for a preview on the games, including predictions from former England, Crystal Palace and Tottenham midfielder Andy Gray and our own Football Insider Graeme Bailey and bet365’s Steve Freeth.
Southampton 20:00 Liverpool
TEAM NEWS: Virgil van Dijk is a doubt to face his former club, but Liverpool hope he should feature – but the game comes too soon for Alex Oxlade-Chamberlain and Joe Gomez.
Southampton’s Jannik Vestergaard and Shane Long should return, but they are without Michael Obafemi and Mario Lemina.
KEY FACT: Southampton are looking to win a third consecutive league match for the first time since May 2016
MATCH ODDS: Southampton 7/1 Draw 19/5 Liverpool 4/9
bet365 Pick: Both Teams To Score @19/20
ANDY SAYS: Liverpool are in this title race to the end and get the win they need here…0-2
GRAEME SAYS: Won’t be an easy test on the South Coast but Liverpool get the win…1-3
Football Index – One to follow: Sadio Mane – Stepping up at the moment, huge value left in him on the Index