Saturday sees what could be one of the games of the season as leaders Manchester City host Tottenham Hotspur in the late kick-off.

City are looking to continue their Premier League winning streak which already stands at 15, and victory will take them 14 points clear at the top as second place Manchester United do not play until Sunday.

Tottenham are looking to maintain their place in the top-four, with Arsenal, Liverpool and Burnley poised to go above them if they lose.

Chelsea have the chance to again move level on points with United as they host Southampton at Stamford Birdge.

As mentioned, sixth placed Burnley – who moved into the top-four in midweek – are looking to return there as they travel to the South Coast to take on Brighton.

Arsenal, currently seventh, could also moved into the top-four with all three points as they welcome out-of-form Newcastle to The Emirates.

The games early kick-off sees one of the league’s form sides Leicester play host to Crystal Palace, who climbed off the foot of the table in midweek.

There is an archetypal six-pointer as Stoke, just two points above the drop-zone, host second from bottom West Ham.

The final game sees Huddersfield travel to Watford.

See below for a preview on each game, including predictions from former England, Crystal Palace and Tottenham midfielder Andy Gray, super agent and former Manchester City ace Barry Silkman, our own Football Insider Graeme Bailey and bet365’s Steve Freeth.

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Leicester City 12:30 Crystal Palace
King Power Stadium
Live On Sky Sports

TEAM NEWS: Timothy Fosu-Mensah is a doubt for Palace, whilst Mamadou Sakho and Joel Ward are missing. Robert Huth and Matty James are again set to miss out for Leicester.
KEY FACT: Leicester are unbeaten in each of their last four Premier League encounters with Crystal Palace
MATCH ODDS: Leicester 10/11 Draw 13/5 Palace 7/2
bet365 Pick: Both Teams To Score @3/4
ANDY SAYS: Leicester are playing well and they should be beating Palace here…2-0
GRAEME SAYS: I think Palace will make a match of it but Leicester are on form…2-1
SILKY SAYS: Leicester will have too much for Palace in this one, no doubt…3-1
FOOTBALLIndex – One to follow: Under £1, Jamie Vardy looks a bargain at 78p

Arsenal 15:00 Newcastle United
Emirates Stadium

TEAM NEWS: Aaron Ramsey and Shkodran Mustafi are set to miss out along with long-term absentee Santi Cazorla. Newcastle have no fresh injury worries but Jonjo Shelvey is suspended after his midweek sending off. KEY FACT: Arsenal have won each of their last nine Premier League matches against Newcastle
MATCH ODDS: Arsenal 2/7 Draw 21/4 Newcastle 11/1
bet365 Pick: Arsenal to win to nil @21/20
ANDY SAYS: I don’t see Arsenal not landing the three points here…2-0
GRAEME SAYS: I think Newcastle might push Arsenal here, but home win…2-1
SILKY SAYS: Comfortable win for Arsenal, no doubt…3-0
FOOTBALLIndex – One to follow: Jack Wilshere back in the team and on the up in the Index

Brighton & Hove Albion 15:00 Burnley
Amex Stadium

TEAM NEWS: Burnley will give late checks on Ben Mee, Matt Lowton and Stephen Ward – all three could be involved. Steve Sidwell remains sidelined with a back problem.
KEY FACT: Brighton are unbeaten in six league matches against Burnley
MATCH ODDS: Brighton 13/8 Draw 2/1 Burnley 11/5
bet365 Pick: Brighton to win @13/8
ANDY SAYS: I think Brighton being at home could just have the edge here…1-0
GRAEME SAYS: Burnley are playing well but being away I will say this could play out in a draw…1-1
SILKY SAYS: I can see Burnley come out on top here, they are on form…1-2
FOOTBALLIndex – One to follow: Steven Defour is playing some great football and at 60p is a bargain

Chelsea 15:00 Southampton
Stamford Bridge

TEAM NEWS: David Luiz again misses out for Chelsea but they hope Alvaro Morata is fit enough to return. Southampton have a fully fit squad to choose from. 
KEY FACT: Chelsea have won each of their last three Premier League matches against Southampton
MATCH ODDS: Chelsea 2/5 Draw 4/1 Southampton 8/1
bet365 Pick: Over 3.5 goals @13/8
ANDY SAYS: I can see a bit of a shock here and Southampton getting something…1-1
GRAEME SAYS: Southampton are poor, Chelsea will brush them aside here…3-0
SILKY SAYS: Comfortable for Chelsea, too good for Southampton…4-0
FOOTBALLIndex – One to follow: Thibaut Courtois is a very interesting option at less than 70p

Stoke City 15:00 West Ham United
bet365 Stadium

TEAM NEWS: West Ham are hoping Cheikhou Kouyate will be fit to face Stoke, but Sam Byram and Jose Fonte remain sidelined. Kurt Zouma is ruled out for Stoke, whilst they will give a late fitness test to Glen Johnson.
KEY FACT: Stoke have never lost to West Ham under Mark Hughes
MATCH ODDS: Stoke 13/10 Draw 23/10 West Ham 5/2
bet365 Pick: Over 2.5 goals @21/20
ANDY SAYS: I quite fancy West Ham to come away with the three points here…0-1
GRAEME SAYS: Will be close, no doubt but Stoke might just edge it…1-0
SILKY SAYS: Tough call, two poor teams really so lets go draw…1-1
FOOTBALLIndex – One to follow:  Just under £1, Marko Arnautovic looks a decent prospect

Watford 15:00 Huddersfield Town
Vicarage Road

TEAM NEWS: Watford have a host of players missing.Tom Cleverley and Marvin Zeegelaar are both suspended, Nathaniel Chalobah, Craig Cathcart, Tommie Hoban, Isaac Success, Younes Kaboul, Stefano Okaka and Will Hughes are all ruled out, while Kiko Femenia, Richarlison and Miguel Britos are major doubts. For Huddersfield, Raji van la Parra is available again after suspension, while Michael Hefele is back from injury. Philip Billing and Jon Stankovic are sidelined.
KEY FACT: Huddersfield have lost five of their last six Premier League matches
MATCH ODDS: Watford 4/5 Draw 11/4 Huddersfield 4/1
bet365 Pick: Under 2.5 goals @4/5
ANDY SAYS: Watford will get the three points here for me…2-0
GRAEME SAYS: Will be a close one, but you have to side with the Hornets here…3-2
SILKY SAYS: I think a home win here, relatively comfortable win…2-0
FOOTBALLIndex – One to follow: Andre Gray is under 70p and just in top-500, surely worth a look

Manchester City 17:30 Tottenham Hotspur
Etihad Stadium
Live On BT Sport

TEAM NEWS: Vincent Kompany and John Stones are set to miss out, although both are nearing fitness. Benjamin Mendy remains sidelined. Davinson Sanchez is suspended for Tottenham and Toby Alderweireld is still out.
KEY FACT: Spurs have won more away Premier League matches at Man City than they have at any other club
MATCH ODDS: Man City 11/20 Draw 18/5 Spurs 5/1
bet365 Pick: Draw @18/5
ANDY SAYS: I don’t see City not winning, not sure Spurs can live with them…3-1
GRAEME SAYS: Be a close game, I think Spurs might be able to claim a draw…2-2
SILKY SAYS: Good game, will be goals, but impossible not to see a City win…3-1
FOOTBALLIndex – One to follow: Harry Kane is over £7 and is third on the Index