The Premier League returns following the international window, and Saturday sees a mouthwatering programme featuring the three sides who so far enjoy a 100% record.
Liverpool, Chelsea and Watford have all won their opening four games, and that could yet become five as none of the trio face each other.
Liverpool put their record on the line first in what is undoubtedly is the game of the weekend as Jurgen Klopp’s men travel to Wembley to face Tottenham Hotspur.
Spurs suffered a shock loss to Watford last time out and will be looking to bounce back against The Hornets.
Maurizio Sarri’s Chelsea will be confident they can continue their fine form as they host win-less Cardiff City at Stamford Bridge.
Watford face another of last season’s top-four as they look to maintain their brilliant start as they welcome Jose Mourinho to Vicarage Road in the late kick-off.
Champions Manchester City will look to keep up the pressure on the top-three as they entertain Fulham at the Etihad.
Newcastle and Huddersfield are both hoping to break their ducks for the season as they have home games to look forward to. The Terriers host Crystal Palace, whilst Arsenal travel to St James’ Park.
The final game of the day sees Leicester travel to the South Coast to face Bournemouth.
See below for a preview on the games, including predictions from former England, Crystal Palace and Tottenham midfielder Andy Gray and our own Football Insider Graeme Bailey and bet365’s Steve Freeth.
Tottenham Hotspur 12:30 Liverpool
Wembley Stadium
TEAM NEWS: Tottenham are without both captain Hugo Lloris and Dele Alli, but they are boosted by the return of Son Heung-min.
Liverpool are set to be without midfielder Adam Lallana, but number 2 keeper Simon Mignolet is fit after a hand injury.
KEY FACT: Matches featuring these two teams have had 22 penalties, more than any other in the competition’s history.
MATCH ODDS: Spurs 21/10 Draw 27/10 Liverpool 13/10
bet365 Pick: Over 2.5 goals & Both Teams To Score @5/6
ANDY SAYS: Liverpool have looked really good this season and see them continuing that fine form at Wembley…1-3
GRAEME SAYS: This will be a cracker, but Tottenham’s injuries could be the telling factor, I will say Liverpool will just sneak this one…1-2
Football Index – One to follow: Christian Eriksen – in great form and one who is heading for the top of the Index.
AFC Bournemouth 15:00 Leicester City
Vitality Stadium
TEAM NEWS: Bournemouth are boosted by the return of Adam Smith from suspension and he should be straight into the starting line-up.
Leicester only have Matty James missing as Claude Puel has big summer signing Caglar Soyuncu fit for the first time since his arrival, and Jamie Vardy returns from suspension.
KEY FACT: Leicester have never beaten Bournemouth in the Premier League
MATCH ODDS: Bournemouth 29/20 Draw 5/2 Leicester 2/1
bet365 Pick: Draw @5/2
ANDY SAYS: Close game but for me I am going with the home side, Eddie Howe’s side have looked decent to me and I think they will grab the three points…2-1
GRAEME SAYS: Leicester back to full strength, I can see them grabbing the win here as they are stronger than Bournemouth…0-2
Football Index – One to follow: Harry Maguire – is on the rise in real life and on the Index
Chelsea 15:00 Cardiff City
Stamford Bridge
TEAM NEWS: Chelsea have a near fully fit squad available with Cesc Fabregas the only major doubt with a knee injury.
Cardiff also have a midfielder struggling with a knee problem in the shape of Icelander Aron Gunnarsson, but they are hoping he is available.
KEY FACT: Chelsea have lost only one of their last 51 home Premier League matches against promoted teams
MATCH ODDS: Chelsea 2/11 Draw 7/1 Cardiff 18/1
bet365 Pick: Both Teams To Score @5/4
ANDY SAYS: Hard to see anything but a home win, and a comfortable one at that – Cardiff just are not good enough…3-0
GRAEME SAYS: You would hope that Cardiff could give Chelsea a good game, but Sarri has The Blues playing so well, they will ease to victory…4-1
Football Index – One to follow: Eden Hazard – he still has a lot of potential to improve when it comes to Index listing
Huddersfield Town 15:00 Crystal Palace
John Smith’s Stadium
TEAM NEWS: Huddersfield captain Jonathan Hogg remains suspended. Juninho Bacuna and Collin Quaner will both be checked on before kick-off.
Christian Benteke, Scott Dann and Connor Wickham are all sidelined for Palace, but Wilfried Zaha and James Tomkins are back in training and could feature.
KEY FACT: Palace have won all three top-flight matches at Huddersfield, keeping a clean sheet on each occasion
MATCH ODDS: Huddersfield 23/10 Draw 21/10 Palace 6/4
bet365 Pick: Both Teams Not To Score @4/5
ANDY SAYS: I think Crystal Palace can do this, Huddersfield are not impressing me…1-2
GRAEME SAYS: Tough call but I think Huddersfield need to win this, and they will – but it will be close…1-0
Football Index – One to follow: Wilfried Zaha – so much potential still left in the Palace man
Man City 15:00 Fulham
Etihad Stadium
TEAM NEWS: Raheem Sterling did not feature for England with a back issue but City expect him to be available, but the game looks set to come too soon for Danilo. Kevin De Bruyne and Claudio BRavo are sidelined.
Fulham are without captain Tom Cairney, along with Neeskens Kebano and Tim Ream.
KEY FACT: The last time Man City lost a Premier League home match to a promoted team was more than 11 years ago
MATCH ODDS: Man City 1/8 Draw 9/1 Fulham 25/1
bet365 Pick: City to win & Both Teams To Score @11/8
ANDY SAYS: This is name your score really, City are going to win – little doubt about it…4-1
GRAEME SAYS: Home win for sure, no doubt about it – Fulham are good, but they can’t live with City – few can…3-0
Football Index – One to follow: Raheem Sterling – doesn’t get the credit he deserves, still a lot of potential
Newcastle United 15:00 Arsenal
St. James’ Park
TEAM NEWS: Salomon Rondon and DeAndre Yedlin could be rested after their late return from international duty, but Matt Ritchie and Jonjo Shelvey are set to return.
Arsenal’s Alex Iwobi is fit again but Sead Kolasinac, Ainsley Maitland-Niles, Laurent Koscielny and Carl Jenkinson are all out.
KEY FACT: Rafa Benitez has won two of this last three Premier League matches against Arsenal
MATCH ODDS: Newcastle 16/5 Draw 14/5 Arsenal 10/11
bet365 Pick: Under 2.5 goals @7/10
ANDY SAYS: I can see a bit of a shock here, I think Newcastle will claim their first win of the season…1-0
GRAEME SAYS: Tough game but I don’t see Arsenal getting beat but Newcastle will claim a point…1-1
Football Index – One to follow: Pierre-Emerick Aubameyang – if he hits form, he is going one way on the Index.
Watford 17:30 Manchester United
Vicarage Road
TEAM NEWS: Watford remain without Gerard Deulofeu and Tom Cleverley as Javi Gracia looks set to name an unchanged side.
Luke Shaw could be involved despite suffering a head injury with England, whilst Marouane Fellaini could also feature but Ander Herrera is sidelined. Marcus Rashford begins his domestic suspension.
KEY FACT:Jose Mourinho has won five of his six Premier League encounters with Watford
MATCH ODDS: Watford 10/3 Draw 13/5 Man Utd 19/20
bet365 Pick: Man United to win @19/20
ANDY SAYS: I can see United’s struggles continuing against a very good Watford, has to be home win for me…2-1
GRAEME SAYS: Watford have been great but surely United have to end their run here, and I see them claiming the away win…1-3
Football Index – One to follow: Romelu Lukaku – starting to show good form, he is every much one to be on