Liverpool look to maintain their perfect start to the new season on Saturday and move back to the top of the Premier League table.
The Reds are currently second in the table only behind the only other team with a 100% record, Chelsea, on goal difference but with Maurizio Sarri’s team not playing until Sunday, it allows Jurgen Klopp’s men to get in first.
They will go top if they avoid defeat to at home to Southampton, indeed they will be looking for a six successive win, a feat they have only ever achieved three times in their history.
Champions Manchester City will also move above Chelsea if they beat win-less Cardiff City in the Welsh capital.
The Bluebirds are one of four teams still to register a win this season, and the other three are also in action. Huddersfield host Leicester, Newcastle travel to London to face Crystal Palace whilst bottom-of-the-table Burnley welcome former boss Eddie Howe and his Bournemouth side to Turf Moor.
Tottenham are looking to put an end to a dismal run of form, which has seen them lose back to back league games, and their opening Champions League clash, as they travel to Brighton.
Manchester United are very much back in form and Wolves as the visitors to Old Trafford as Jose Mourinho meets fellow countryman Nuno.
The other game is the opening clash of the weekend as Fulham play host to Watford – who are looking to bounce back after their first loss of the season last week.
See below for a preview on the games, including predictions from former England, Crystal Palace and Tottenham midfielder Andy Gray and our own Football Insider Graeme Bailey and bet365’s Steve Freeth.
Fulham 12:30 Watford
Craven Cottage
TEAM NEWS: Neeskens Kabano and Tim Ream remain sidelined for Fulham and they hoping Tom Cairney might be available, but he is still considered doubtful.
Watford are still without key midfielders Gerard Deulofeu and Tom Cleverley.
KEY FACT: In-form Watford captain Troy Deeney has scored four goals in his two league appearances against Fulham.
MATCH ODDS: Fulham 11/8 Draw 12/5 Watford 15/8
bet365 Pick: Fulham to win @11/8
ANDY SAYS: Watford are still playing really well despite defeat last week and I can see them taking the points off of Fulham here…1-2
GRAEME SAYS: Good local-ish derby here, and I can only see a draw with them cancelling each other out…1-1
Football Index – One to follow: Roberto Pereyra – just outside the top-200, the Watford midfielder is on the up and offers great value
Burnley 15:00 AFC Bournemouth
Turf Moor
TEAM NEWS: Steven Defour, Robbie Brady, Ben Gibson and Nick Pope are all sidelined for Burnley.
Bournemouth have a near fully fit squad to choose from with Charlie Daniels a long-term absentee.
KEY FACT: Burnley have lost their last four league matches
MATCH ODDS: Burnley 15/8 Draw 21/10 Bournemouth 31/20
bet365 Pick: Burnley win/draw – no bet @10/11
ANDY SAYS: Burnley’s poor run has to come to an end and I think it does here with a narrow win…1-0
GRAEME SAYS: Tough call, the former says away win but you have to think that Burnley get their opening win here…2-1
Football Index – One to follow: Callum Wilson – so much potential with this lad, an England call-up could see him shoot up the Index.
Cardiff City 15:00 Manchester City
Cardiff City Stadium
TEAM NEWS: Man City are without long-term injury victims Kevin De Bruyne, Claudio Bravo and Danilo. They hope Benjamin Mendy will be able to start.
Nathan Mendez-Laing is out, but Josh Murphy and Aron Gunnarsson should be ready to return along with Harry Arter – who has had a stomach bug.
KEY FACT: Man City are unbeaten in their last 21 Premier League matches against promoted sides
MATCH ODDS: Spurs 21/10 Draw 27/10 Liverpool 13/10
bet365 Pick: Draw Half Time/Man City Full Time @3/1
ANDY SAYS: I have said all along how l didn’t rate Cardiff and Man City will give them a good going over here…1-4
GRAEME SAYS: Cardiff will make life very hard for City here, but Pep’s boys will win – but only just…0-2
Football Index – One to follow: Raheem Sterling – still under-rated, in real life and on the Index, well worth a look.
Crystal Palace 15:00 Newcastle United
Selhurst Park
TEAM NEWS: Connor Wickham, Scott Dann, Pape Souare and Christian Benteke are all ruled out for Palace.
Newcastle are sweating over the fitness of key duo Jonjo Shelvey and Jamaal Lascelles and could give both fitness tests.
KEY FACT: Crystal Palace have won one of their last 10 PL matches against Newcastle
MATCH ODDS: Palace Evens Draw 12/5 Newcastle 11/4
bet365 Pick: Both Teams To Score @19/20
ANDY SAYS: Clearly I would like my old side to win this but I think Newcastle will get something, and I think there will be goals…2-2
GRAEME SAYS: Palace looked very good at Huddersfield and with Zaha on form, they win this for me…2-0
Football Index – One to follow: Wilfried Zaha – a must for any portfolio really, full of potential and only going to go one way
Leicester City 15:00 Huddersfield Town
King Power Stadium
TEAM NEWS: Leicester boss Claude Puel has a near fully fit squad to choose from with only Matty James through injury, but captain Wes Morgan is suspended.
Huddersfield are hoping Erik Durm, Colin Quaner, Juninho Bacuna and Ramadhan Sobhi will all be fit.
KEY FACT: Leicester have won eight of their last nine league matches against Huddersfield
MATCH ODDS: Leicester 11/20 Draw 14/5 Huddersfield 11/2
bet365 Pick: Under 2.5 goals @8/11
ANDY SAYS: Has to be a home win, Leicester just look far too strong for Huddersfield for me…2-0
GRAEME SAYS: Difficult to see how Huddersfield are gong to get something here and I don’t think they will…2-0
Football Index – One to follow: Harry Maguire – is there a better defensive prospect in world football?
Liverpool 15:00 Southampton
Anfield
TEAM NEWS: Dejan Lovren and long-term injury victim Alex Oxlade-Chamberlain miss out for Liverpool but they hope former Saints ace Adam Lallana could return.
Southampton are without top-scorer Danny Ings as he can’t face his parent club
KEY FACT: Liverpool have kept a clean sheet in each of their last four Premier League matches against Southampton
MATCH ODDS: Liverpool 1/5 Draw 11/2 Southampton 12/1
bet365 Pick: Liverpool to win to nil @10/11
ANDY SAYS: Liverpool are going to win this, little doubt about it for me – easy home win…3-0
GRAEME SAYS: I don’t think this will be easy at all, but has to be a Liverpool win…2-0
Football Index – One to follow: Danny Ings – he may not be playing but he is having a great time and needs to be looked at
Manchester United 15:00 Wolverhampton Wanderers
Old Trafford
TEAM NEWS: Man United are without suspended duo Nemanja Matic and Marcus Rashford. Marcos Rojo, Phil Jones and Ander Herrera are all doubtful.
Wolves could have Ivan Cavaleiro back from his back injury, and if he is then Nuno could have a full squad available to him.
KEY FACT: Wolves could win a third match in-a-row, and if they do it would be the firs time in the top-flight since March 1980
MATCH ODDS: Man Utd 4/7 Draw 11/4 Wolves 5/1
bet365 Pick: Under 2.5 goals @19/20
ANDY SAYS: Could be a cracker this one with Jose v Nuno – and I see Wolves getting something here…1-1
GRAEME SAYS: I think this is going to be a great game, and I think United will just do enough…2-1
Football Index – One to follow: Romelu Lukaku – hitting form, one to keep an eye on and stick with, plenty of value.
Brighton & Hove Albion 17:30 Tottenham Hotspur
AMEX Stadium
TEAM NEWS: Tottenham are waiting on Dele Alli and Momo Sissoko, and hope they will be ready to return but Hugo Lloris is sidelined.
Jose Izquierdo could return for Brighton this weekend but Pascal Gross misses out.
KEY FACT: Brighton have gone two goals down in their last two Premier League fixtures but avoided defeat both times
MATCH ODDS: Brighton 7/2 Draw 14/5 Spurs 8/11
bet365 Pick: Spurs to win @8/11
ANDY SAYS: I am going with my former club here to get back on track and claim a win…1-3
GRAEME SAYS: This could be a tough ride for Spurs, but I will give them the benefit of the doubt…0-2
Football Index – One to follow: Christian Eriksen – in great form and one who is heading for the top of the Index.
