Premier League leaders Liverpool could extend their lead at the top to nine points in their final game of 2019.
Liverpool host fifth place Arsenal in a mouthwatering contest at Anfield in the late kick-off on the day.
Tottenham, who moved into second place on Boxing Day, have chance to make sure they move into 2019 in that spot as they host Wolves at Wembley.
Leicester can easily stake a claim for being the form side in world football with the scalps of Chelsea and Manchester City in successive games and they will finish the year in 7th if they beat Cardiff at the King Power.
Watford have a chance to move into seventh, but to do that they need to beat Newcastle at Vicarage Road.
At the foot of the table, there is a huge ‘six point’ clash as bottom placed Huddersfield travel to second from bottom Fulham.
The game’s other day sees Brighton host Everton with the Seagulls looking to end a run of four games without a win.
See below for a preview on the game, including predictions from former England, Crystal Palace and Tottenham midfielder Andy Gray and our own Football Insider Graeme Bailey and bet365’s Steve Freeth.
Brighton & Hove Albion 15:00 Everton
Amex Stadium
TEAM NEWS: Lewis Dunk returns from suspension for Brighton who are still without Alireza Jahanbakhsh and Jose Izquierdo.
Everton have a near fully fit squad with Ademola Lookman than only player missing.
KEY FACT: Brighton have won only one of their last 11 league matches against Everton
MATCH ODDS: Brighton 5/2 Draw 12/5 Everton 5/4
bet365 Pick: Draw @12/5
ANDY SAYS: I can see Brighton’s struggles continuing with a decent Everton win…1-3
GRAEME SAYS: I tipped Brighton to take a point off Arsenal and I can see the same thing here…1-1
Football Index – One to follow: Solly March – fine young winger with lots of potential
Fulham 15:00 Huddersfield Town
Craven Cottage
TEAM NEWS: Andre-Frank Zambo Anguissa is Fulham’s only injury absentee.
Danny Williams, Tommy Smith, Aaron Mooy and Adbelhamid Sabiri all remain long-term absentees whilst Rajiv van La Parra will not feature as he is about to leave for Middlesbrough.
KEY FACT: Fulham have yet to lose a top-flight home match against Huddersfield
MATCH ODDS: Fulham 11/10 Draw 23/10 Huddersfield 3/1
bet365 Pick: Both Teams To Score @Evens
ANDY SAYS: Huge game this and I think Fulham will get the big win, but will be close…2-1
GRAEME SAYS: Tough call but just have to give Fulham the edge here…1-0
Football Index – One to follow: Ryan Sessegnon – a player full of potential and ability
Leicester City 15:00 Cardiff City
King Power Stadium
TEAM NEWS: Matty James is still working on his fitness, whilst Daniel Amartey is only the only long-term injury for Leicester.
Callum Paterson and Jazz Richards could be back for Cardiff, but Kenneth Zohore and Danny Ward will not be involved.
KEY FACT: Leicester have won seven of their last 10 Premier League games against newly promoted teams
MATCH ODDS: Leicester 4/7 Draw 16/5 Cardiff 11/2
bet365 Pick: Under 2.5 goals @10/11
ANDY SAYS: Leicester will seal a comfortable home win here, not a problem…3-0
GRAEME SAYS: Leicester have been in great form, they will take the three points…2-0
Football Index – One to follow: Jamie Vardy – showing that he is a top class striker, could yet be value here
Tottenham Hotspur 15:00 Wolverhampton Wanderers
Wembley Stadium
TEAM NEWS: Wolves could have a fully fit squad to choose from if Leander Dendoncker and Diogo Jota recover.
Dele Alli and Moussa Sissoko have joined a lengthy absentee list at Spurs, which already consists of Eric Dier, Jan Vertonghen, Vincent Wanyama and Moussa Dembele.
KEY FACT: Wolves are winless in five Premier League matches against Spurs
MATCH ODDS: Spurs 4/11 Draw 17/4 Wolves 9/1
bet365 Pick: Under 2.5 goals @11/10
ANDY SAYS: This won’t be easy for Spurs but I think my former club is going to win…2-0
GRAEME SAYS: Has to be a Tottenham win, they have been hugely impressive…2-0
Football Index – One to follow: Harry Kane – no holding back one of the best strikers in the world
Watford 15:00 Newcastle United
Vicarage Road
TEAM NEWS: Christian Kabasele, Andre Gray, Will Hughes, Adalberto Penaranda and Sebastian Prodl will all miss out for Watford.
Newcastle are set to recall striker Salomon Rondon, who was rested in the 4-0 defeat at Liverpool.
South Korean midfielder Ki Sung-yueng is away on international duty.
KEY FACT: Watford have won four of their last five Premier League meetings with Newcastle
MATCH ODDS: Watford 5/6 Draw 11/4 Newcastle 15/4
bet365 Pick: Geard Deulofeu to score anytime @11/5
ANDY SAYS: Watford are a strange team and Newcastle could have enough in them to get a point…1-1
GRAEME SAYS: I find it hard to put a case for Newcastle getting anything, Watford win…2-1
Football Index – One to follow: Roberto Pereyra – a fabulous player, full of value
Liverpool 17:30 Arsenal
Anfield
TEAM NEWS: Alberto Moreno, Joel Matip and Joe Gomez remain sidelined, but Alex Oxlade-Chamberlain has returned to training but is still weeks away from playing. James Milner could feature.
Captain Laurent Koscielny should be available but Shkodran Mustafi, but Hector Bellerin and Rob Holding are ruled out.
KEY FACT: Arsenal have not won in their last five league games at Anfield
MATCH ODDS: Liverpool 1/2 Draw 15/4 Arsenal 6/1
bet365 Pick: Liverpool to win & Under 3.5 goals @8/5
ANDY SAYS: This could be a super game but has to be a Liverpool win…2-0
GRAEME SAYS: I see a few goals here, but mainly for Liverpool – they will finish the season in style…3-1
Football Index – One to follow: Roberto Firmino – one who has considerable value remaining
