Only one place to start with the Premier League this weekend and that is on Merseyside for arguably the biggest game in English football as Liverpool host bitter rivals Manchester United.

United make the trip across Lancashire in the opening fixture of the weekend as they look to maintain their unbeaten start to the season.

United are currently second on goal-difference with neighbours Manchester City leading the way, and they are also in action on Saturday as they host Stoke City at the Etihad.

Tottenham Hotspur find themselves in third place, despite the fact they have yet to win at home this season at their temporary Wembley home but they will be looking to put that right as they host Bournemouth.

The top-four are all in action on Saturday, with Champions Chelsea making the short trip across the capital to face bottom-of-the-table, pointless and goalless Crystal Palace.

Watford host Arsenal in the late game, with both teams just outside the top-four – victory for either could take lift them their, depending on earlier results.

Burnley could also challenge for a place in the top-four, should they overcome West Ham United at Turf Moor.

Swansea, third from bottom, host Huddersfield looking for their first home win of the season, whilst victory for the visitors would lift them back into the top-half of the table.

See below for a run-down on the games, including predictions from former England, Crystal Palace and Tottenham midfielder Andy Gray, leading agent Barry Silkman and our own Football Insider Graeme Bailey.

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Liverpool 12:30 Man Utd
Anfield
Live On Sky Sports

TEAM NEWS: Sadio Mane is out for six weeks with a damaged hamstring suffered whilst on international duty. Manchester United could be short in midfielder with Marouane Fellaini, Michael Carrick and Paul Pogba all sidelined.
KEY FACT: Liverpool are winless in six Premier League matches against Manchester United
MATCH ODDS: Liverpool 33/20 Draw 23/10 Man Utd 8/5
ANDY SAYS: A good game this one close so I will go with high-scoring draw…2-2
GRAEME SAYS: I don’t see how Liverpool can win this, Man Utd should have enough…1-3
SILKY SAYS: A good game, but a close one – I will just side with United…1-2
FOOTBALLIndex – One to follow: Romelu Lukaku is over £5 now and plenty of potential to go further

Burnley 15:00 West Ham
Turf Moor

TEAM NEWS: Dean Marney, Nahki Wells and Jonathan Walters are all sidelined for Burnley. Javier Hernandez, Pedro Obiang and Edmilson Fernandes should all be fit to make the trip, but James Collins is ruled out.
KEY FACT: West Ham have won their last four Premier League matches against Burnley
MATCH ODDS: Burnley 17/10 Draw 21/10 West Ham 7/4
ANDY SAYS: Another close call, but think West Ham should get something so draw…1-1
GRAEME SAYS: I believe Burnley are player better, won’t be a lot of goals…1-0
SILKY SAYS: Tough one, I don’t see either playing good football…1-1
FOOTBALLIndex – One to follow: At just 75p, Javier Hernandez remains a very good buy

Crystal Palace 15:00 Chelsea
Selhurst Park

TEAM NEWS: N’Golo Kante is out for a number of weeks with a thigh injury, whilst Alvaro Morata is sidelined with a hamstring injury. Danny Drinkwater is yet to make his Chelsea debut and is approaching full fitness. Scott Dann and James Tomkins could return, but forwards Wilfried Zaha, Christian Benteke and Connor Wickham are still out. Reuben Loftus-Cheek is ineligible to face his parent club.
KEY FACT: Crystal Palace have won only one of their previous eight home Premier League matches against Chelsea
MATCH ODDS: Palace 15/2 Draw 7/2 Chelsea 2/5
ANDY SAYS: Tough game for my former club, I just can’t see them getting anything…0-2
GRAEME SAYS: This could be closer than people think and Palace might get that first goal…1-2
SILKY SAYS: Comfortable Chelslea win here, could be a heavy defeat…0-3 
FOOTBALLIndex – One to follow: Eden Hazard is now just over £4 – now back fully fit, has to be a top buy!

Man City 15:00 Stoke
Etihad Stadium

TEAM NEWS: Sergio Aguero remains sidelined with his broken rib, but Fabian Delph could feature and fill in at left-back again. Stoke’s captain Ryan Shawcross remains sidelined with a back injury, whilst Joe Allen is a doubt after suffering his head injury playing for Wales.
KEY FACT: Man City have kept a clean sheet in eight of their nine Premier League home matches against Stoke
MATCH ODDS: Man City 1/8 Draw 15/2 Stoke 14/1
ANDY SAYS: Don’t see City having any issues here and be a comfortable home win…4-1
GRAEME SAYS: Stoke may make it difficult, but don’t see them coming up short…3-0
SILKY SAYS: Could be a cricket score here, and I think City will hit them for six…6-0
FOOTBALLIndex – One to follow: Under £3.50 for Gabriel Jesus – how is that not a bargain?

Swansea 15:00 Huddersfield
Liberty Stadium

TEAM NEWS: Renato Sanches and Wilfried Bony are major doubts for the home side. Nathan Dyer is fit again following a lengthy spell on the sidelines with an Achilles injury. Danny Williams is fit again, whilst Steve Mounie is unlikely to be risked. Michael Hefele, Kasey Palmer and Collin Quaner.
KEY FACT: This is the first ever top-flight meeting between these two sides
MATCH ODDS: Swansea 23/20 Draw 2/1 Huddersfield 11/4
ANDY SAYS: I can see the home side just coming out on top here…1-0
GRAEME SAYS: Close contest, but I think Huddersfield will get something from this…1-1
SILKY SAYS: Haven’t been too impressed with either recently but will just go with Swansea…2-1
FOOTBALLIndex – One to follow: Tammy Abraham looks an interesting prospect at 91p

Spurs 15:00 Bournemouth
Wembley Stadium

TEAM NEWS: Serge Aurier is back after suspension. Moussa Dembele could feature after an ankle problem but Danny Rose, Victor Wanyama and Erik Lamela are sidelined. Long-term absentee Callum Wilson is back for Bournemouth and could play at Wembley. Tyrone Mings, Ryan Fraser and Adam Federici are all sidelined.
KEY FACT: Game is set to break the highest attendance in Premier League history.
MATCH ODDS: Spurs 1/5 Draw 11/2 Bournemouth 14/1
ANDY SAYS: My former team won’t have a problem in grabbing the win here…3-0
GRAEME SAYS: Tottenham will claim their first win under the big Arch here…3-0
SILKY SAYS: Comfortable win here for Spurs, opening win with ease…4-0
FOOTBALLIndex – One to follow: Dele Alli at under £4 – boom, get on this boy!

Watford 17:30 Arsenal
Vicarage Road
Live On BT Sport

TEAM NEWS: Sebastian Prodl is doubtful with a hamstring problem. Younes Kaboul, Isaac Success and Nathaniel Chalobah are all ruled out. Danny Welbeck and Mesut Ozil are available again, but Shkodran Mustafi is out. Sead Kolasinac and Laurent Koscielny will have fitness tests.
KEY FACT: Watford have made their best-ever start to a Premier League season
MATCH ODDS: Watford 4/1 Draw 3/1 Arsenal 8/13
ANDY SAYS: Arsenal won’t have it their won way but will get the win…0-2
GRAEME SAYS: I am a huge fan of Marco Silva – can see them getting a draw here…1-1
SILKY SAYS: Arsenal will be too good, they will get the win…1-3
FOOTBALLIndex – One to follow: Jack Wilshere at just over £1 – if he is in contention, a sure fire bargain