With Premier League leaders Liverpool on duty at the Club World Cup – reigning champions Manchester City and second placed Leicester City take centre stage.

Man City and Leicester face off in the final game of the day, in what is no doubt the game of the weekend. A win for Leicester would move them to within seven points of Liverpool and seven ahead of City.

The day’s opening game is probably the most fascinating as Everton and Arsenal clash, with both set to be under new management next week with Carlo Ancelotti and Mikel Arteta ready to take up their positions.

Seventh placed Sheffield United’s wonderful run of form means victory for them at Brighton will see them moved up to fifth as both Manchester United and Tottenham Hotspur don’t play until Sunday.

Victory for Wolverhampton Wanderers at second from bottom Norwich will also see them move about United and Spurs, for at least 24 hours.

There is a real six-pointer at Villa Park as fourth bottom Aston Villa welcome third bottom Southampton – with only goal-difference separating the two clubs at the moment.

There are also two big games in mid-table with Newcastle hosting Crystal Palace and Bournemouth taking on Burnley.

See below for a preview on the games, including predictions from former England, Crystal Palace and Tottenham midfielder Andy Gray and our own Football Insider Graeme Bailey and bet365’s Steve Freeth.

Everton 12:30 Arsenal
Goodison Park

TEAM NEWS: Everton are hoping to have Gylfi Sigurdsson, Djibril Sidibe and Fabian Delph available, but Jean-Philippe Gbamin, Theo Walcott, Morgan Schneiderlin, Lucas Digne and Andre Gomes are sidelined. | Arsenal are without Granit Xhaka and Kieran Tierney, but Rob Holding, Hector Bellerin, Dani Ceballos and Sead Kolasinac could be involved.
KEY FACT: Everton have won four of their last five home Premier League matches against London sides
MATCH ODDS: Everton 11/8 Draw 11/4 Arsenal 7/4
bet365 Pick: Both Teams To Score & Over 2.5 goals @8/11
ANDY SAYS: Everton have been playing well since Marco Silva left and I think that continues…2-0
GRAEME SAYS: Two new bosses are set to arrive and they will see their teams play out a draw…1-1
Football Index – One to follow: Richarlison – A huge talent and is back to form

AFC Bournemouth 15:00 Burnley
Vitality Stadium

TEAM NEWS: Callum Wilson and Josh King could return for Bournemouth, but they remain without a host of players, including Nathan Ake, Adam Smith, Steve Cook, Harry Wilson, Arnaut Danjuma Groeneveld, Charlie Daniels and Lloyd Kelly.
KEY FACT: Bournemouth are looking to secure back-to-back Premier League victories for the first time since September
MATCH ODDS: Bournemouth 11/8 Draw 12/5 Burnley 2/1
bet365 Pick: Under 2.5 goals @10/11
ANDY SAYS: This will be a close one, but Bournemouth are on a high after their win at Chelsea so I see them landing a win…1-0
GRAEME SAYS: Tough call here, but I think Burnley might just hold out for a draw – but don’t expect a classic…0-0
Football Index – One to follow: Harry Wilson – The Liverpool loanee is looking like a class act

Aston Villa 15:00 Southampton
Villa Park

TEAM NEWS: Jed Steer is ruled out for Villa, who are also likely to be without Tyrone Mings and Keinan Davis. | Yann Valery misses out for Southampton but they hope to have Moussa Djenepo, Sofiane Boufal and Kevin Danso available.
KEY FACT: Villa are looking to avoid losing four consecutive league matches for the first time since February 2017
MATCH ODDS: Villa 7/5 Draw 13/5 Southampton 9/5
bet365 Pick: Over 3.5 goals @6/4
ANDY SAYS: Two teams who are not playing well, and I think they play out a draw…1-1
GRAEME SAYS: Close game and a huge one for both teams but I think Villa have the edge here…2-1
Football Index – One to follow: John McGinn – Has the potential to go to the top

Brighton & Hove Albion 15:00 Sheffield United
Amex Stadium

TEAM NEWS:Jose Izquierdo and Solly March miss out for Brighton, but they should have Aaron Connolly available. | John Fleck is suspended for United, but he could very well be the only player missing as Callum Robinson should recover from his recent illness.
KEY FACT: Sheffield United are looking to record three consecutive Premier League victories for the first time since 1993
MATCH ODDS: Brighton 6/5 Draw 9/4 Sheff Utd 5/2
bet365 Pick: Neal Maupay to score first goal @5/1
ANDY SAYS: Sheff Utd are playing so well, I think they will claim a point here…1-1
GRAEME SAYS: Brighton are a strong force at home and I see them getting the win here…2-0
Football Index – One to follow: Neal Maupay – Emerging as a huge Premier League talent

Newcastle United 15:00 Crystal Palace
St. James’ Park

TEAM NEWS: Miguel Almiron and Jonjo Shelvey should be available for Newcastle, but they are without a host of players including Matt Ritchie, Allan Saint-Maximin, Jamaal Lascelles, Ki Sung-Yeung and Ciaran Clark. | Mamadou Sakho is suspended for Palace, meaning he misses out along with Gary Cahill, Andros Townsend, Joel Ward and Jeffrey Schlupp but Patrick van Aanholt and Jairo Riedewald could feature.
KEY FACT: Newcastle are unbeaten in their last seven home Premier League matches, their best run since 2012
MATCH ODDS: Newcastle 11/8 Draw 21/10 Palace 7/4
bet365 Pick: Under 1.5 goals @7/4
ANDY SAYS: Palace are playing well and I think my former club make the long trip and get the win…1-2
GRAEME SAYS: Close call but Newcastle are playing well and at home I think they to take the win…2-1
Football Index – One to follow: Sean Longstaff – Emerging as a big talent

Norwich City 15:00 Wolverhampton Wanderers
Carrow Road

TEAM NEWS: Norwich have doubts over Teemu Pukki and Grant Hanley, but Timm Klose and Josip Drmic miss out. | Morgan Gibbs-White and Wily Boly are sidelined for Wolves.
KEY FACT: Wolves have lost just one of their last 12 Premier League games
MATCH ODDS: Norwich 11/4 Draw 14/5 Wolves 10/11
bet365 Pick: Raul Jimenez to score first goal @15/4
ANDY SAYS: Wolves are a class act and they will collect the three points here…1-3
GRAEME SAYS: Norwich are not playing great and they won’t be able to stop Wolves here…0-2
Football Index – One to follow: Adama Traore – Looking like a world-class prospect

Manchester City 17:30 Leicester City
Etihad Stadium

TEAM NEWS: John Stones, Sergio Aguero and David Silva could be involved for City, but Aymeric Laporte and Leroy Sane are ruled out. | Leicester have a near fully fit squad with only Matty James missing.
KEY FACT: Man City have won four of their last five Premier League meetings with Leicester
MATCH ODDS: Man City 4/11 Draw 17/4 Leicester 13/2
bet365 Pick: Leicester Double Chance @9/4
ANDY SAYS: Close game and should be a good one, and I think they cancel each other out…1-1
GRAEME SAYS: Am going with the champions here, but it will be close…2-1
Football Index – One to follow: Kevin De Bruyne – Showing amazing form and looks as good as anything on the planet