The top-six are all in action on Saturday, with leaders Manchester City looking to maintain their strangle-hold at the summit.

City – the only unbeaten side left in the Premier League – are five points clear at the top and they could increase that to seven points with victory at West Brom.

City’s lead can’t go to eight points, as the clubs in second and third, Man United and Tottenham – play each other in the day’s opening game in what promises to be the match of the weekend.

Champions Chelsea in fourth travel to second from bottom Bournemouth looking to close the gap on the top-three, likewise Arsenal will be hoping to do the same, as they host Swansea.

Watford are looking to continue their excellent start to the season and they will fancy their chances against out-of-form Stoke City.

Liverpool are looking for their first league win in more than a month as Huddersfield come to Anfield.

At the wrong end of the table and we have something of a six-pointer with bottom-of-the-table Crystal Palace hosting under-fire Slaven Bilic’s West Ham.

See below for a run-down on the games, including predictions from former England, Crystal Palace and Tottenham midfielder Andy Gray, leading agent Barry Silkman, our own Football Insider Graeme Bailey and bet365’s Steve Freeth.

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Manchester United 12:30 Tottenham Hotspur 
Old Trafford
Live On Sky Sports

TEAM NEWS: Paul Pogba, Michael Carrick, Marouane Fellaini and Michael Carrick are all out for United, whilst Marcus Rashford and Eric Bailly are both doubtful. Harry Kane has been ruled out for Spurs whilst Victor Wanyama and Erik Lamela remain sidelined, but Mousa Dembele and Danny Rose could both return to the starting line-up.
KEY FACT: Spurs, who beat Man Utd in May, can record consecutive PL victories against the Red Devils for the first time
MATCH ODDS: Man Utd 11/10 Draw 23/10 Spurs 5/2
bet365 Pick: Draw @23/10
ANDY SAYS: A good game, and will be close but I think United might just sneak it…2-1
GRAEME SAYS: I don’t see many goals here, and I think we could see a goalless draw…0-0
SILKY SAYS: This could go either way but I will just go with Jose to claim the win…2-1
FOOTBALLIndex – One to follow: Harry Kane has broken through the £7 barrier, and he still has plenty of room to increase

Arsenal 15:00 Swansea City
Emirates Stadium

TEAM NEWS:  Shkodran Mustafi, Calum Chambers, Danny Welbeck and David Ospina are all ruled out for Arsenal. Martin Olsson, Wilfried Bony and Renato Sanches all miss out for Swansea.
KEY FACT: Arsenal can win back-to-back Premier League matches against Swansea for the first time
MATCH ODDS: Arsenal 1/5 Draw 11/2 Swansea 12/1
bet365 Pick: Arsenal to win to nil @20/21
ANDY SAYS: The Gunners will be too strong for Swansea, has to be a home win…3-0
GRAEME SAYS: I don’t see how Swansea will get anything here, has to be Arsenal…2-0  
SILKY SAYS: Arsenal will win and with something to spare, comfortable home win…5-0
FOOTBALLIndex – One to follow: Alexis Sanchez down to under £6, still full of potential

Crystal Palace 15:00 West Ham United 
Selhurst Park

TEAM NEWS: Christian Benteke remains sidelined, whilst Lee Chung-yong is a major doubt but James McArthur should be available. Andre Ayew and Andy Carroll are set to start for West Ham.
KEY FACT: Manuel Lanzini has scored in all four of his PL matches against Crystal Palace
MATCH ODDS: Palace 13/10 Draw 21/10 West Ham 9/4
bet365 Pick: Manuel Lanzini to score anytime @3/1
ANDY SAYS: A tough derby, I will go with a draw…1-1
GRAEME SAYS: I think Palace might just grab this one, be close but home win…2-0
SILKY SAYS: West Ham are the better team on paper and I think they will just grab the win…1-2
FOOTBALLIndex – One to follow: Manuel Lanzini is a great price at under £1

Liverpool 15:00 Huddersfield Town
Anfield

TEAM NEWS: Georginio Wijnaldum is ready to return for Liverpool but Adam Lallana and Nathaniel Clyne miss out again. Philip Billing, Jon Gorenc Stankovic, Michael Hefele and Kasey Palmer are all out. Elias Kachunga is fit to return.
KEY FACT: Liverpool have lost only one of their last 42 Premier League home matches against newly-promoted sides 
MATCH ODDS: Liverpool 2/11 Draw 6/1 Huddersfield 11/1
bet365 Pick: Liverpool to win & BTTS @15/8
ANDY SAYS: Huddersfield won’t make it easy but home win for sure…3-1
GRAEME SAYS: You have to go with Liverpool, but they may find it harder than they think…2-1
SILKY SAYS: Comfortable home win, don’t see Liverpool being troubled too much…3-0
FOOTBALLIndex – One to follow: Philippe Coutinho at just over £5 still looks a great buy

Watford 15:00 Stoke City 
Vicarage Road

TEAM NEWS: Roberto Pereyra has joined a lengthy Watford injury list which already includes Sebastian Prodl, Younes Kaboul, Isaac Success, Nathaniel Chalobah and Craig Cathcart. Xherdan Shaqiri and Tom Edwards should be ready to return for Stoke but Stephen Ireland and Bruno Martins Indi are still out.
KEY FACT: Stoke’s Peter Crouch has three goals in his two Premier League starts against Watford
MATCH ODDS: Watford Evs Draw 12/5 Stoke 11/4
bet365 Pick: Both Teams To Score @3/4
ANDY SAYS: Stoke have been so poor, I can only see Watford claiming the win..2-1
GRAEME SAYS: I love what Marco Silva is doing and you have to go with Watford here…3-1
SILKY SAYS: I think Watford will be too strong, and win this…2-0
FOOTBALLIndex – One to follow: Jack Butland at under a £1 is a great buy

West Bromwich Albion 15:00 Manchester City
The Hawthorns

TEAM NEWS: West Brom defender Craig Dawson has been ruled out for eight weeks. Vincent Kompany and Benjamin Mendy both miss out for City.
KEY FACT: Manchester City are unbeaten in their last 15 Premier League matches against West Brom
MATCH ODDS: WBA 9/1 Draw 5/1 Man City 1/4
bet365 Pick: Man City to win and BTTS @15/8
ANDY SAYS: Easy away win, no stopping Man City here…0-4
GRAEME SAYS: Hard to see City not winning, WBA could sneak a draw but have to go City…1-3
SILKY SAYS: Man City to win all day, just a matter of how many they will score…1-4
FOOTBALLIndex – One to follow: Surely David Silva at £1.21 is a great buy

AFC Bournemouth 17:30 Chelsea
Vitality Stadium
Live On BT Sport

TEAM NEWS: Danny Drinkwater could make his Premier League debut for Chelsea but N’Golo Kante and Victor Moses remain sidelined. Josh King and Jermain Defoe are expected to return for Bournemouth but Tyrone Mings is out with a back problem.
KEY FACT: Eden Hazard has scored four goals in four PL appearances against the Cherries
MATCH ODDS: Bournemouth 9/2 Draw 3/1 Chelsea 4/7
bet365 Pick: Over 4.5 on Cards @6/5
ANDY SAYS: Comfortable away win here, easy for Chelsea…0-3
GRAEME SAYS: I could see a bit of a shock here and maybe Bournemouth grabbing the win…2-1
SILKY SAYS: I don’t see Chelsea not winning here, and winning comfortably…0-3
FOOTBALLIndex – One to follow: Criminal that Eden Hazard is not even in the INDEX top-ten, get on him