Half-a-dozen Premier League games on Tuesday kick-off a packed midweek programme, including a big capital derby clash between Chelsea and Arsenal.

Champions Manchester City travel across the Pennines to visit Sheffield United in a tough looking encounter.

There is also a big relegation six-pointer as Aston Villa take on Watford.

See below for a preview on the games, including predictions from former England, Crystal Palace and Tottenham midfielder Andy Gray and our own Football Insider Graeme Bailey and bet365’s Steve Freeth.

AFC Bournemouth 19:30 Brighton & Hove Albion
Vitality Stadium

TEAM NEWS: Jefferson Lerma and Lloyd Kelly should be fit, whilst Steve Cook is suspended joining Jack Stacey, Joshua King, Charlie Daniels, Chris Mepham, David Brooks, Arnaut Danjuma Groeneveld and Junior Stanislas on the sidelines. | Leon Balogun, Dan Burn and Jose Izquierdo are ruled out for Brighton.
KEY FACT: Bournemouth have won four of their last five home league matches against Brighton
MATCH ODDS: Bournemouth 15/8 Draw 12/5 Brighton 29/20
bet365 Pick: Draw @12/5
ANDY SAYS: Bad news for Bournemouth here as Brighton snatch the honours…0-1
GRAEME SAYS: Bournemouth really need the win in this one so will give them the benefit of the doubt…2-1
Football Index – One to follow: Callum Wilson – The England striker really needs to step-up if he wants to make squad for Euros

Aston Villa 19:30 Watford
Villa Park

TEAM NEWS: John McGinn, Thomas Heaton, Jed Steer, Keinan Davis and Wesley are all injured for Villa. | Watford could have Kiko Femenia available, whilst Danny Welbeck is back in training, but The Hornets are without a host of players including Tom Cleverley, Will Hughes, Sebastian Prodl, Daryl Janmaat and Ismaila Sarr.
KEY FACT: Aston Villa have kept a clean sheet in all three of their evening kick-offs at home in the Premier League this season
MATCH ODDS: Villa 9/5 Draw 5/2 Watford 29/20
bet365 Pick: Draw @5/2
ANDY SAYS: I think Watford will be too strong for Villa, given the form they are in…1-2
GRAEME SAYS: Tough call here, but I think they share the spoils although it could go either way…1-1
Football Index – One to follow: Jack Grealish – A huge talent and must be in the next England squad

Crystal Palace 19:30 Southampton
Selhurst Park

TEAM NEWS: Max Meyer will be fit for Palace, whilst they hope Christian Benteke could be available but they are without Andros Townsend, Jeffrey Schlupp, Patrick van Aanholt and Mamadou Sakho. Luka Milivojevic is still suspended. | Jan Bednarek and Yan Valery are the only players missing for Southampton.
KEY FACT: Crystal Palace have not lost since before Christmas
MATCH ODDS: Palace 7/4 Draw 9/4 Southampton 13/8
bet365 Pick: Over 2.5 goals @6/5
ANDY SAYS: Good game this one between two teams in good form but I think Southampton will have enough to snatch a point here…1-1
GRAEME SAYS: I believe that Palace will end a run of four draws with victory in this one…2-0
Football Index – One to follow: Wilfried Zaha – Brilliant last week and showed what he is capable of

Everton 19:30 Newcastle United
Goodison Park

TEAM NEWS: Andre Gomes and Jean-Philippe Gbamin are ruled out for Everton, but they could be the only ones missing as they hope Michael Keane, Alex Iwobi, Richarlison and Gylfi Sigurdsson will be available. | Andy Carroll could possibly make the game, but Newcastle are without a host of players including Dwight Gayle, Javi Manquillo, Jack Colback, Yoshinori Muto, DeAndre Yedlin, Ki Sung-Yeung, Paul Dummett and Jetro Willems.
KEY FACT: Everton have lost only one of their last 15 home league fixtures against Newcastle
MATCH ODDS: Everton 11/20 Draw 31/10 Newcastle 5/1
bet365 Pick: Under 2.5 goals @10/11
ANDY SAYS: Everton will take the win in this one, I think being at home will give it to them…2-1
GRAEME SAYS: I see Carlo Ancelotti’s team getting the three points in this one…2-0
Football Index – One to follow: Miguel Almiron – Starting to show some real form

Sheffield United 19:30 Manchester City
Bramall Lane

TEAM NEWS: The Blades could boast a near fully fit squad, with the only doubt being David McGoldrick. | Aymeric Laporte, Benjamin Mendy and John Stones all have a chance of being involved, but Leroy Sane is still ruled out.
KEY FACT: Man City are looking to win three consecutive away league matches at Sheffield United for the first time since 1907
MATCH ODDS: Sheff Utd 6/1 Draw 4/1 Man City 2/5
bet365 Pick: Sheff Utd +1 @7/4
ANDY SAYS: City will turn on the style in this one and have far too much for United…1-3
GRAEME SAYS: Excellent game and I think United’s style will be hard for City to break down, so draw…1-1
Football Index – One to follow: Raheem Sterling – One of the Premier League’s best

Chelsea 20:15 Arsenal
Stamford Bridge

TEAM NEWS: Reece James and Marco Alonso should make it for Chelsea, but Christian Pulisic and Ruben Loftus-Cheek remain sidelined. | Arsenal could have Sokratis available, but Pierre Emerick-Aubameyang is still suspended whilst Calum Chambers, Kieran Tierney, Sead Kolasinac and Reiss Nelson remain sidelined.
KEY FACT: Frank Lampard is looking to become the first English Chelsea manager to do the league double against Arsenal since Dave Sexton in 1970
MATCH ODDS: Chelsea 8/11 Draw 29/10 Arsenal 7/2
bet365 Pick: Tammy Abraham to score first @3/1
ANDY SAYS: I am backing Chelsea in this one, good game but I see them bouncing back with a win…2-0
GRAEME SAYS: I think that Arsenal will go for this and they will be rewarded with a point…1-1
Football Index – One to follow: Reece James – A huge talent and likely heading for an England call-up