The games come thick and fast in the Premier League at the start of the year with six games including Chelsea and Manchester United opening their 2019 accounts.
Fourth placed Chelsea begin at home as they host Southampton at Stamford Bridge.
Man United are fine fettle under interim boss Ole Gunnar Solskjaer with three wins from three and he will be looking to keep that run going at Newcastle.
In-form Wolves are looking for a fourth win in five games as they entertain Crystal Palace at Molineux.
Bottom of the table Huddersfield are looking to end a run of seven successive defeats as they take on Burnley at the John Smith’s Stadium.
West Ham could move into the top half of the table with victory over Brighton at the London Stadium.
The final game of the day sees Watford travel to the South Coast to take on Bournemouth.
See below for a preview on the games, including predictions from former England, Crystal Palace and Tottenham midfielder Andy Gray and our own Football Insider Graeme Bailey and bet365’s Steve Freeth.
AFC Bournemouth 19:45 Watford
Vitality Stadium
TEAM NEWS: Simon Francis, Adam Smith, Lewis Cook and Dan Gosling are all long-term absentees for Bournemouth, whilst Nathan Ake is a major doubt.
Christian Kabasele, Sebastian Prodl, Daryl Janmaat and Andre Gray are all ruled out for Watford.
KEY FACT: Bournemouth are looking to start a year with a win for the first time since 2012
MATCH ODDS: Bournemouth 13/8 Draw 13/5 Watford 17/10
bet365 Pick: Both Teams To Score & Over 2.5 goals @21/20
ANDY SAYS: I can see Watford claiming the win here…1-2
GRAEME SAYS: I tough call this one, but I believe Bournemouth could claim the win…2-0
Football Index – One to follow: Ryan Fraser – has been in fine form for The Cherries, and is one to keep an eye on
Chelsea 19:45 Southampton
Stamford Bridge
TEAM NEWS: Pedro, Cesc Fabregas, Ruben Loftus-Cheek, Callum Hudson-Odoi and Danny Drinkwater are all sidelined for Chelsea and Olivier Giroud is struggling with an ankle problem.
Ryan Bertrand is close to fitness but is unlikely to face his former side, whilst Michael Obafemi also remains out. Pierre-Emile Hojbjerg is suspended.
KEY FACT: Southampton have won three of their 19 PL visits to Stamford Bridge
MATCH ODDS: Chelsea 2/7 Draw 5/1 Southampton 11/1
bet365 Pick: Both Teams To Score @19/20
ANDY SAYS: Chelsea won’t slip up here, three points coming for Sarri’s men…2-0
GRAEME SAYS: Hard to see how Southampton can get something from this, and I don’t think they will…3-1
Football Index – One to follow: Eden Hazard – one of the world’s best but still some real value
Huddersfield Town 19:45 Burnley
John Smith’s Stadium
TEAM NEWS: Aaron Mooy, Danny Williams, Abdelhamid Sabiri and Tommy Smith are all sidelined for Huddersfield.
Matt Lowton returns after a ban, whilst Robbie Brady is fit again, but Steven Defour, Stephen Ward, Aaron Lennon and Nick Pope all remain out.
KEY FACT: All three Premier League meetings between these two have been drawn
MATCH ODDS: Huddersfield 5/4 Draw 21/10 Burnley 29/10
bet365 Pick: Draw @21/10
ANDY SAYS: A close game and big one, but I am just edging towards the home side…1-0
GRAEME SAYS: A huge clash here, a real ‘six-pointer’ but can see it ending in a draw…0-0
Football Index – One to follow: Alex Pritchard – a very good player, who has some real upside
West Ham United 19:45 Brighton & Hove Albion
London Stadium
TEAM NEWS: Samir Nasri could get his debut, whilst Pablo Zabaleta and Robert Snodgrass are doubtful with knocks but they have a lengthy injury list with Javier Hernandez, Jack Wilshere, Ryan Fredericks, Andriy Yarmolenko, Carlos Sanchez, Winston Reid and Manuel Lanzini all remain sidelined.
Jose Izquierdo remains sidelined for Brighton but Anthony Knockaert is back in the squad. Goalkeeper Mat Ryan and winger Alireza Jahanbakhsh are unavailable as they are on international duty at the Asian Cup.
KEY FACT: West Ham have lost five and won just one of their seven top-flight matches against Brighton
MATCH ODDS: West Ham 21/20 Draw 5/2 Brighton 29/10
bet365 Pick: West Ham to win @21/20
ANDY SAYS: I see West Ham grabbing the three points here but it will be close…1-0
GRAEME SAYS: Another tough call for sure, but have to give West Ham the benefit and just about doing it…2-1
Football Index – One to follow: Manuel Lanzini – he will be back from injury soon so invest now ready for his return
Wolverhampton Wanderers 19:45 Crystal Palace
Molineux
TEAM NEWS: Wolves will have a fully fit squad to choose from if Diogo Jota and Adama Traore come through to feature.
Max Meyer and Connor Wickham are both in contention to start for Palace, so the only player missing for Roy Hodgson is Christian Benteke.
KEY FACT: Wolves have lost only one of their past 12 top-flight matches against Crystal Palace
MATCH ODDS: Wolves 21/20 Draw 23/10 Palace 16/5
bet365 Pick: Both Teams To Score – No @4/5
ANDY SAYS: I can see my former team going to Wolves and getting a point…1-1
GRAEME SAYS: Palace won’t get anything here for me, Wolves will be far too strong…2-0
Football Index – One to follow: Wilfried Zaha – still a top talent and one who should be looked at
Newcastle United 20:00 Manchester United
St. James’ Park
TEAM NEWS: Newcastle have doubts over defenders Federico Fernandez and Ciaran Clark remains a doubt with an ankle problem. Florian Lejuene is back in training but remains out. Ki Sung-yeung is away at the Asian Cup.
Alexis Sanchez will be involved for United, whilst Marcus Rashford should be OK, but Chris Smalling and Marcos Rojo are sidelined whilst Eric Bailly is suspended.
KEY FACT: Newcastle are looking for consecutive top-flight home victories against Man Utd for the first time since 1987
MATCH ODDS: Newcastle 19/4 Draw 31/10 Man Utd 13/20
bet365 Pick: Man Utd win & Under 2.5 goals @10/3
ANDY SAYS: Man Utd are playing too well, they will bag all three points here…1-3
GRAEME SAYS: I think Newcastle will make it hard, but United just to edge it…1-2
Football Index – One to follow: Marcus Rashford – in great form and well worth investing in
