Manchester City could go 14 points clear at the top of the Premier League on Wednesday.
City, who some Bookmakers have already paid out on, travel to South Wales to face Swansea. Victory for City will give them a 15th top-flight win in a row, which would beat Arsenal’s 14-match record run in 2002.
Swansea dropped to the foot-of-the-table on Tuesday, but victory for them could take them above 16th placed Newcastle – who are looking to end their dismal run of form at home to Everton.
Manchester United will be looking to try and make sure City’s lead at the top is not extended as they host Bournemouth at Old Trafford.
Liverpool are looking to move back into the top-four, as they take on West Brom – who now find themselves in the bottom-three.
West Ham face a second successive London derby as they host Arsenal, and they will hoping to follow up their success over Chelsea with another win as they look to move out of the drop-zone.
Leicester are looking for a fourth successive win as Claude Puel’s returns to his former club Southampton.
Victory for Leicester could take them within touching distance of Tottenham, who are looking for back-to-back wins at Wembley as they host Brighton.
See below for a preview on each game, including predictions from former England, Crystal Palace and Tottenham midfielder Andy Gray, super agent and former Manchester City ace Barry Silkman, our own Football Insider Graeme Bailey and bet365’s Steve Freeth.
Newcastle United 19:45 Everton
St. James’ Park
TEAM NEWS: Paul Dummett remains unavailable for Newcastle. Everton have no fresh injury worries but Yannick Bolasie, Ramiro Funes Mori, Seamus Coleman, James McCarthy, Ross Barkley and Leighton Baines all miss out.
KEY FACT: Newcastle have lost six of their last seven league matches against Everton
MATCH ODDS: Newcastle 7/5 Draw 23/10 Everton 9/4
bet365 Pick: Everton Draw No Bet @6/5
ANDY SAYS: I think Newcastle will get back to winning way with three points here…2-1
GRAEME SAYS: I don’t see many goals and not sure that Newcastle will win…0-0
SILKY SAYS: Tough call, has to be a draw for me, Big Sam will get something…1-1
FOOTBALLIndex – One to follow: Still in the top-200, Wayne Rooney is looking good at £1.20
Southampton 19:45 Leicester City
St. Mary’s Stadium
TEAM NEWS: Southampton have a fully fit squad after Cedric Soares returned to training. Robert Huth and Matty James are back in training but won’t feature at St Mary’s.
KEY FACT: Southampton have lost only one of their 11 Premier League home matches against Leicester
MATCH ODDS: Southampton 11/10 Draw 12/5 Leicester 29/10
bet365 Pick: Draw @12/5
ANDY SAYS: I think Leicester will get something from this, it will be close…1-1
GRAEME SAYS: I haven’t been impressed with Southampton this season, Leicester for the win…0-2
SILKY SAYS: I can see goals in this, a high-scoring draw…2-2
FOOTBALLIndex – One to follow: At £1.62, Riyad Mahrez remains in the top-100 and a good buy
Swansea City 19:45 Manchester City
TEAM NEWS: Wayne Routledge is doubtful for Swansea. Kyle Bartley is back in training but won’t be involved. Vincent Kompany has been ruled out for City, and that is the only injury worry for the league leaders.
KEY FACT: Man City have won 75% of their Premier League matches against Swansea
MATCH ODDS: Swansea 14/1 Draw 11/2 Man City 1/4
bet365 Pick: Both Teams To Score @19/20
ANDY SAYS: Comfortable Man City win, don’t see them not winning…1-4
GRAEME SAYS: Swansea won’t be a walkover, win for Man City, but not a hammering…1-2
SILKY SAYS: No way Man City are not winning this, three easy point for my former team…0-4
FOOTBALLIndex – One to follow: At £3.74 and 16th in the Index, Kevin De Bruyne is the highest rated City player
Liverpool 20:00 West Bromwich Albion
TEAM NEWS: Joel Matip and Alberto Moreno are both missing for Liverpool, but Adam Lallana could return for the home side. Gareth Barry and James Morrison are both been ruled out, whilst they will assess Matt Phillips and Nacer Chadli before kick-off.
KEY FACT: Liverpool are unbeaten in their last eight Premier League matches against West Brom
MATCH ODDS: Liverpool 2/9 Draw 6/1 WBA 14/1
bet365 Pick: Half time Draw Full time Liverpool @3/1
ANDY SAYS: Don’t see Liverpool being challenged here, comfortable win…3-0
GRAEME SAYS: West Brom could be a tough nut to crack, but home win…2-0
SILKY SAYS: Easy win for Liverpool, I don’t think West Brom are getting near them…3-0
FOOTBALLIndex – One to follow: At £4.05 and just outside the top-ten, Mo Salah is a player to get on
Manchester United 20:00 AFC Bournemouth
TEAM NEWS: Marcos Rojo is a doubt due to a cut to his head. Eric Bailly is ruled out with a groin problem whilst Paul Pogba remains suspended. Phil Jones is back to full fitness. Adam Smith is back after suspension, but Tyrone Mings has suffered a setback with his back problem.
KEY FACT: Bournemouth are unbeaten in their last four away matches
MATCH ODDS: Man Utd 2/7 Draw 5/1 Bournemouth 12/1
bet365 Pick: Man Utd to win and Both Teams To Score @2/1
ANDY SAYS: Should be a relatively easy three points for United…2-0
GRAEME SAYS: United should have far too much for Bournemouth…4-1
SILKY SAYS: Has to be a comfortable home win, they should bounce back with victory…3-0
FOOTBALLIndex – One to follow: Romelu Lukaku at £4.57 is United’s highest rated player on the index
Tottenham Hotspur 20:00 Brighton & Hove Albion
TEAM NEWS: Neither side has any new injury worries. Spurs remain without Toby Alderweireld, Victor Wanyama and the suspended Davinson Sanchez. Steve Sidwell is Brighton’s only absentee.
KEY FACT: Brighton have attempted fewer shots than any other side this season
MATCH ODDS: Spurs 1/4 Draw 11/2 Brighton 14/1
bet365 Pick: Spurs to win to nil @5/6
ANDY SAYS: My old team should win here, three points coming Spurs’ way…4-1
GRAEME SAYS: I think Spurs could find Brighton a tough task here, but should win…2-1
SILKY SAYS: Three points coming for Spurs, comfortable win…4-0
FOOTBALLIndex – One to follow: At £3.87, Dele Alli has nearly dropped out of the top-20
West Ham United 20:00 Arsenal
Live On BT Sport
TEAM NEWS: Michail Antonio is fit, but James Collins, Cheikhou Kouyate and Edmilson Fernandes are set to miss out. Shkodran Mustafi and Aaron Ramsey are both sidelined for Arsenal.
KEY FACT: This will be West Ham’s 100th home PL London derby, winning 36 of the 99
MATCH ODDS: West Ham 9/2 Draw 17/5 Arsenal 8/13
bet365 Pick: Draw @17/5
ANDY SAYS: Arsenal to just claim a narrow win, but it won’t be easy…1-2
GRAEME SAYS: West Ham could get something here, I think they will get a point…1-1
SILKY SAYS: I can see a lot of goals here, but you have to go with Arsenal…2-4
FOOTBALLIndex – One to follow: Available at £1, West Ham’s best player Manuel Lanzini is a great option