The all new UEFA Nations League kicks-off this week and Spain are favourites to take the title.

The Nations League replaces friendlies with competitive matches, allowing nations to play against supposedly equal ranked teams.

The four group winners of the top-ranked League A qualify for the UEFA Nations League finals in June 2019.

For the remaining sides, there is promotion and relegation to play for, not to mention a potential route to EURO 2020.

England have been made 10/1 shots to follow up their semi-final appearance at the World Cup.

Gareth Southgate’s men will earn a semi-final place for the first running of the competition if they top their group of three, which also involves Spain and Croatia.

BoyleSports make the Three Lions narrow favourites at 17/10 to kick off their campaign with a victory against Spain at Wembley on Saturday with the Spaniards 9/5 outsiders.

England have also been backed in to 11/2 from 6/1 to score three or more goals on the night after Spain shipped goals in three of their four World Cup fixtures in the summer. Goalkeeper David De Gea kept only one clean sheet against Iran and has subsequently leaked three goals to both Tottenham and Brighton this season for Manchester united.

A Group 1 clash in League A between the last two World Cup Champions, France and Germany, is the highlight of the first round of games with the Germans 6/4 favourites to bounce back from their World Cup disappointment with a win on home soil.

Wales meanwhile were backed into 10/11 odds-on shots from Even money to earn a victory on Ryan Giggs’ first competitive night in charge, with opponents Republic of Ireland now out at 7/2 as they head to Cardiff with a depleted squad.

Lawrence Lyons, spokesperson for BoyleSports said: “England have plenty of momentum going into the new competition and we’d be surprised if Gareth Southgate took these games lightly. His side are seeing plenty of interest at 10/1 to win it outright and although they’re kicking off against the tournament favourites, they could go off shorter by the time they kick off against Spain on Saturday.”

Nations League Fixtures:
Matchday 1: 6–8 September 2018
Matchday 2: 9–11 September 2018
Matchday 3: 11–13 October 2018
Matchday 4: 14–16 October 2018
Matchday 5: 15–17 November 2018
Matchday 6: 18–20 November 2018
Finals: 5–9 June 2019
UEFA EURO 2020 play-off draw: 22 November 2019
UEFA EURO 2020 play-offs: 26–31 March 2020