England are odds on to beat Ireland in Dublin next week and make history.

The Six Nations returns following a two-week break with the Calcutta Cup match-up at Twickenham between England and Scotland the highlight of round 4.

England were rated 1/1000 to beat Italy, but the game at Twickenham was anything but a walk in the park for Eddie Jones's undefeated outfit.

A brilliant second-half showing helped Scotland to a 29-13 win over Wales at Murrayfield, whilst Ireland got the better of France at the Aviva Stadium.

England's march to a consecutive Six Nations crown will be tested by Italy at Twickenham this weekend, but it is the other two matches which look to have all the interest.

France's hard fought 22-16 win over Scotland has seen England's odds for Six Nations glory reduced further.

England left it late to beat Wales in Cardiff as their odds to win the Six Nations were shortened further to even money.

It is the second week of the Six Nations and champions England are looking to maintain their run of form in Wales.

England are an even shorter price to lift the Six Nations once again after nearest rivals Ireland were humbled by Scotland.